Fatal Elizabethkingia Meningosepticacholangitis Following Biliary Stent Placement

Abstract

Elizabethkingia (E.) meningosepticais a ubiquitous gram-negative bacillus belonging to the genus Chryseobacteriumand has been reported to cause nosocomial infections in both the immunocompromised and immunocompetent patients. E. meningoseptica can colonize the biliary tree after endoscopic procedures; and cholangitis, caused by this organism, is associated with a favorable prognosis. Here, we report a fatal case of cholangitis secondary to E. meningoseptica that developed following biliary stent placement. This case suggests that E. meningoseptica can be a cause of potentially fatal biliary tract infections in patients who undergo biliary tract endoscopic procedures. Clinicians must not disregard this organism as a contaminant (or colonizer) as a delay in diagnosis and treatment can lead to a fatal outcome, as seen in this case.

Core-Proteomics-Based Annotation of Antigenic Targets and Reverse-Vaccinology-Assisted Design of Ensemble Immunogen against the Emerging Nosocomial Infection-Causing Bacterium Elizabethkingia meningoseptica

“…According to epidemiological reports, Taiwan is the emerging geographical center of E. meningoseptica infections over the last decade [2,3,16]. Several other reports declare Saudi Arabia, Pakistan, India, Brazil, and Kuwait to have many cases [6,[17][18][19][20][21]. Treatment for E. meningoseptica infections should be based on the minimum inhibitory concentration (MIC) results from susceptibility tests.…”