Fat Necrosis of the Breast

Hassan, Hebatallah Hassan Mamdouh; El, Amr; Bary, Amany Abdel; Naguib, N

doi:10.1016/j.acra.2017.12.019

Cited by 9 publications

(7 citation statements)

References 16 publications

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“…In some rare cases, they can result in tenderness, bruising, skin tethering, dimpling and nipple retraction. In addition, breast abnormalities may remain unchanged, enlarge, regress, or resolve [1]. Taboada et al, [3] showed that in about 47.4% of cases fat necrosis would be appeared as cystic masses which shown in Table 1 (In accordance with Prasanti et al [4]).…”

Section: Introductionmentioning

confidence: 64%

“…Some of the common causes of FN are radiotherapy, surgery or trauma, particularly one associated with anticoagulation therapy. It is mostly associated with post-operative or radiation therapy [1]. It is difficult to distinguish the clinical and radiographic appearance of breast fat necrosis from that of malignancy.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, a multidisciplinary team needs to be involved in this process. The common imaging features of fat necrosis are summarized in Table 2 [1, 2, 14, 15, 17, 18, 20].…”

Section: Introductionmentioning

confidence: 99%

“…Women with breast hypertrophy also suffer from physical symptoms including psychosocial problems and back pain. These problems can lead to activation of lipolytic enzymes and rupture of blood vessel [1]. Adipose tissue consists of triglyceride-containing cells.…”

Section: Introductionmentioning

confidence: 99%

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Fat necrosis in the Breast: A systematic review of clinical

et al. 2019

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Breast fat necrosis (FN) originates from aseptic fat saponification, which is a typical lipid cyst or a spiculated lesion called mammographic presentation which mimics malignancy. In order to avoid biopsy, it would be necessary to identify the spectrum of fat necrosis appearances. A systematic research was conducted in October 2018 by using PubMed, MEDLINE, Embase, Google Scholar databases and Google to search for science literature published after 2004. Therefore, the aim of this systematic review, it is that the FN can provide radiologists, surgeons, and oncologists with better insight and help them manage the condition efficiently.

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Section: Introductionmentioning

confidence: 64%

Section: Introductionmentioning

confidence: 99%

“…Moreover, a multidisciplinary team needs to be involved in this process. The common imaging features of fat necrosis are summarized in Table 2 [1, 2, 14, 15, 17, 18, 20].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fat necrosis in the Breast: A systematic review of clinical

et al. 2019

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“…Also, T1-weighted sequence is highly important in diagnosis of post-operative fat necrosis which is a common complication following breast surgery and radiation therapy. The presence of fat signal in a lesion revealed sensitivity of 98.04%, specificity of 100%, PPV of 100%, and NPP of 96.88% for diagnosis of fat necrosis [10].…”

Section: Introductionmentioning

confidence: 99%

Detection of recurrent breast carcinoma using unenhanced breast MRI

EL-Adalany

EL-Metwally

2020

Egypt J Radiol Nucl Med

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Background: Early detection of locally recurrent breast carcinoma has been shown to significantly improve longterm survival. Surgery and radiation therapy made treated breast prone to several modifications. This can complicate the interpretation of ultrasound and mammographic images, especially when local recurrence is suspected. The aim of this work is to assess the role of unenhanced MRI (T1WI, T2WI, STIR, and DWI) in differentiating recurrent breast cancer from benign post-operative lesions. Results: The presence of fat SI within the lesions had 100% sensitivity, 90.9% specificity, 94.1% PPV, 100% NPV, and 96.2% accuracy in differentiating fat necrosis from recurrent breast carcinoma. A cutoff ADC value of 1 × 10-3 mm 2 / s for observer one had 80% sensitivity, 90.9% specificity, and 88.9% accuracy in diagnosis of recurrent breast carcinoma. For observer two, a cutoff ADC value of 1.25 × 10-3 mm2/s had sensitivity of 80%, specificity of 88.6%, and diagnostic accuracy of 87.03% in differentiating recurrent breast carcinoma from benign post-operative changes. Unenhanced MRI had 81.8% sensitivity, 97.7% specificity, 90% PPV, 95.5% NPV, and 94.5% accuracy in the diagnosis of recurrent breast carcinoma. Conclusion: Unenhanced MRI including T1WI, T2WI, STIR, DWI, and ADC map had high sensitivity, specificity, and diagnostic accuracy in diagnosis of recurrent breast carcinoma and differentiating it from benign post-operative changes.

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Proton MR spectroscopy in the breast: Technical innovations and clinical applications

Fardanesh

Marino

Avendaño

et al. 2019

Magnetic Resonance Imaging

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Proton magnetic resonance spectroscopy (MRS) is a promising noninvasive diagnostic technique for investigation of breast cancer metabolism. Spectroscopic imaging data may be obtained following contrast‐enhanced MRI by applying the point‐resolved spectroscopy sequence (PRESS) or the stimulated echo acquisition mode (STEAM) sequence from the MR voxel encompassing the breast lesion. Total choline signal (tCho) measured in vivo using either a qualitative or quantitative approach has been used as a diagnostic test in the workup of malignant breast lesions. In addition to tCho metabolites, other relevant metabolites, including multiple lipids, can be detected and monitored. MRS has been heavily investigated as an adjunct to morphologic and dynamic MRI to improve diagnostic accuracy in breast cancer, obviating unnecessary benign biopsies. Besides its use in the staging of breast cancer, other promising applications have been recently investigated, including the assessment of treatment response and therapy monitoring. This review provides guidance on spectroscopic acquisition and quantification methods and highlights current and evolving clinical applications of proton MRS. Level of Evidence 5 Technical Efficacy: Stage 5 J. Magn. Reson. Imaging 2019.

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Fat Necrosis of the Breast

Cited by 9 publications

References 16 publications

Fat necrosis in the Breast: A systematic review of clinical

Fat necrosis in the Breast: A systematic review of clinical

Detection of recurrent breast carcinoma using unenhanced breast MRI

Proton MR spectroscopy in the breast: Technical innovations and clinical applications

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