Fat Content of Lumbar Paraspinal Muscles in Patients with Chronic Low Back Pain and in Asymptomatic Volunteers: Quantification with MR Spectroscopy

Mengiardi, Bernard; Schmid, Marius R.; Boos, Norbert; Pfirrmann, Christian W. A.; Brunner, Florian; Elfering, Achim; Hodler, Juerg

doi:10.1148/radiol.2403050820

Cited by 246 publications

(229 citation statements)

References 44 publications

Supporting

Mentioning

208

Contrasting

Order By: Relevance

“…In this scale, axial cross-section of lumber 4 -5 intervertebral area on T2-weighted MRI sequences is evaluated and the degree of atrophy and fatty degeneration of multifidus, longissimus, and psoas muscle isdetermined (Figure 2). Accordingly: Grade 0: normal muscle, grade 1: some fatty streaks, grade 2: less than 50% fatty muscle atrophy, grade 3: 50% fatty muscle atrophy, and grade 4: greater than 50% fatty muscle atrophy [7]. In our case, fatty degeneration was dominant in nearly all of the lumbar paraspinal muscles and there was alsovolume loss and fatty degeneration in psoas muscle (Grade 4).…”

Section: Discussionsupporting

confidence: 44%

“…A literature review of this subject revealed that fatty degeneration of paravertebral muscles occurs particularly in the multifidus muscle, that two posterior muscle groups accompany degeneration in a limited number of cases, and that most of the cases have grade 3 and 4 degeneration (Figure 3). In grade 4 patients, fatty degeneration is present, particularly in interstitial connective tissue elements, and fat mass is more than muscle mass [7]. In our case, the muscles in the posterior paravertebral region were observed to have atrophied completely, and there was almost no muscle tissue.…”

Section: Discussionmentioning

confidence: 44%

See 1 more Smart Citation

Rare Case of Complete Fatty Degeneration of the Paraspinal Muscle in a Patient with Low Back Pain

Atçı¹

2016

Ann Clin Anal Med

View full text Add to dashboard Cite

ÖzetBel ve sırt ağrılarının etyopatogenezi her zaman ortaya konulamamakta, bazen klinisyenler klinik bulgularla radyolojik tetkikler arasında ilişki kuramamaktadırlar.Klinisyenler bel ve sırt ağrılarında görüntülemede çoğunlukla vertebra cismi, intervertebral disk ve faset eklemlere odaklanma eğilimindedir. Ancak görüntülemeler-de lomber omurga stabilizasyonunda önemli rol oynayan paravertebral kaslar gö-zardı edilmemelidir. Lomber bölgede yağ depoziti miktarındaki artış ve kas kitlesinin azalması makroskopik olarak kas dejenerasyonu bulgusudur. Bu olgu sunumu kronik bel ağrısı nedenli tarafımıza başvuran ve görüntüleme raporunda 2 seviye bulging dışında patolojik bulgu olmayan bir hastanın tarafımızca incelenen görün-tülemesinde paravertebral adelelerde kas dokusunun tamamen yağlı dejenerasyona uğradığı ve lomber omurga stabilitesinde önemli rol oynayan kasların volümle-rini kaybederek atrofi olduğu görülmesi nedenli yapılmıştır. Anahtar KelimelerKronik Bel Ağrısı; Paraspinal Adale; Yağlı Dejenerasyon AbstractThe ethiopathogenesis of low back pain cannot always be demonstrated and sometimes clinicians cannot establish a relationship between clinical symptoms and radiological examinations. Clinicians tend to focus on vertebral body, intervertebral discs, and facet joints on imaging in low back pain. However, the paravertebral muscles that play an important role in lumbar spine stabilization should not be underestimated on imaging. The increase in the amount of fat deposited in the lumbar region and the reduction of muscle mass are macroscopic findings of muscle degeneration. In this case report, we present a patient with chronic low back pain who had been reported to have no pathological findings except 2 levels of bulging on previous imaging and who was then diagnosed as having complete fatty degeneration and atrophy of the paravertebral muscles after reevaluation of her imaging results.

show abstract

Section: Discussionsupporting

confidence: 44%

Section: Discussionmentioning

confidence: 44%

Rare Case of Complete Fatty Degeneration of the Paraspinal Muscle in a Patient with Low Back Pain

Atçı¹

2016

Ann Clin Anal Med

View full text Add to dashboard Cite

show abstract

“…Atrophy and fat infiltrates are identified in patients [16][17][18][19][20][21] and following experimentally induced lesions in a porcine model. 22 However, human studies describing lumbar MFI report inconsistent findings: An association with LBP was demonstrated in some 18,[23][24][25][26] but not in others. 13,16 One explanation for discrepant findings is the influence of age on muscle composition.…”

Section: 9mentioning

confidence: 99%

Age- and Level-Dependence of Fatty Infiltration in Lumbar Paravertebral Muscles of Healthy Volunteers

Crawford

Filli

Elliott

et al. 2015

AJNR Am J Neuroradiol

187

167

View full text Add to dashboard Cite

show abstract

“…TrA and LM contractions normally occur in an anticipatory manner prior to limb movement in healthy adults, whereas contraction of TrA and LM is delayed or attenuated in patients with LBP 67,[73][74][75][76][77] . In addition, fatty infiltration and atrophy of Type I and II muscle fibers occur in the LM of persons with LBP [70][71][72][78][79][80] . It has been reported that lumbar stabilization exercise programs can normalize the functional and morphological changes in patients with LBP through improving the strength, endurance, and/or motor control of the abdominal and lumbar trunk musculature [81][82][83][84][85][86] .…”

Section: Discussionmentioning

confidence: 99%

The Efficacy of Spinal Decompression via DRX3000 Combined with a Spinal Mobilization and a Lumbar Stabilization Exercise Program for Patients with Discogenic Low Back Pain

Ma¹,

Kim

2010

J Phys Ther Sci

View full text Add to dashboard Cite

Abstract.[Purpose] The purpose of this study was to determine the effects of motorized spinal decompression using the DRX3000 system (Axiom Worldwide, Tampa, FL, USA) combined with spinal mobilization as well as lumbar stabilization exercises on patients with discogenic low back pain (LBP).[Subjects] A total of 30 adults with discogenic LBP (mean age, 34.06 ± 6.41 years; age range, 28-48 years; 14 males, 16 females) volunteered to participate in this study.[Methods] A 4-week course of spinal decompression treatment combined with motorized flexion-distraction mobilization and lumbar stabilization exercises were administered to the participants for 6 days per week for the first two weeks, and four times per week for two additional weeks. The entire treatment consisted of 20 visits over a 4-week period. Comparisons of changes in the Oswestry Disability Index (ODI) and straight leg raise (SLR) test at pre-intervention, after 10 treatment sessions, and at discharge (after 20 treatment sessions) were analyzed.[Results] There were significant improvements in the outcome measures of ODI score and SLR test after 10 and 20 sessions of spinal decompression treatment combined with spinal mobilization and lumbar stabilization exercises as compared with the pre-intervention.[Conclusion] Spinal decompression treatment combined with spinal mobilization and lumbar stabilization exercises significantly improved the clinical outcome measures of ODI score and SLR test in patients with LBP secondary to intervertebral disc herniation.

show abstract

Fat Content of Lumbar Paraspinal Muscles in Patients with Chronic Low Back Pain and in Asymptomatic Volunteers: Quantification with MR Spectroscopy

Abstract: Proton MR spectroscopy demonstrates a significantly higher fat content in the multifidus muscle in patients with chronic LBP than in asymptomatic volunteers. No difference was detected with a semiquantitative grading system.

Cited by 246 publications

References 44 publications

Rare Case of Complete Fatty Degeneration of the Paraspinal Muscle in a Patient with Low Back Pain

Rare Case of Complete Fatty Degeneration of the Paraspinal Muscle in a Patient with Low Back Pain

Age- and Level-Dependence of Fatty Infiltration in Lumbar Paravertebral Muscles of Healthy Volunteers

The Efficacy of Spinal Decompression via DRX3000 Combined with a Spinal Mobilization and a Lumbar Stabilization Exercise Program for Patients with Discogenic Low Back Pain

Contact Info

Product

Resources

About