Fat clearance of upper gastrointestinal resection specimens increases lymph node yield and may result in nodal upstaging

Griffin, Jon; Bunning, Clare; Dube, A

doi:10.1136/jclinpath-2018-205457

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…51 Fat clearance of resection specimens may increase lymph node yield and result in nodal upstaging. 52 D1 lymph node resections include the removal of the perigastric lymph nodes (Figure 2, A), whereas D2 resections include the removal of perigastric lymph nodes and the lymph nodes along the left gastric, common hepatic, and splenic arteries, and the celiac axis (Figure 2, B).…”

Section: Tumor Regressionmentioning

confidence: 99%

Data Set for Reporting Carcinoma of the Stomach in Gastrectomy

Shi

Badgwell

Grabsch

et al. 2021

Archives of Pathology &Amp; Laboratory Medicine

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Context.— A standardized detailed surgical pathology report is the cornerstone of gastric cancer management. Objective.— To guide management and prognostication for patients with gastric carcinomas globally, the International Collaboration on Cancer Reporting aimed to produce an evidence-based international pathology reporting data set with a panel of globally recognized expert pathologists and clinicians. Design.— Based on published guidelines/data sets for gastric carcinomas, a working draft was developed by the chair of the expert panel of pathologists and clinicians. The draft was then circulated to the panel and discussed in a series of teleconferences and email communications until consensus was achieved. The draft data set was uploaded on the International Collaboration on Cancer Reporting Web site for public comment. The data set was reviewed in consideration of the feedback, and a final version was approved by the panel. Results.— This data set was developed for gastrectomy specimens for primary gastric carcinomas, including neuroendocrine carcinomas and mixed neuroendocrine-nonneuroendocrine neoplasms. Well-differentiated neuroendocrine tumors, nonepithelial malignancies, and secondary tumors were excluded from this data set. The final data set contains 15 core (required) elements and 8 noncore (recommended) elements. A commentary is provided for each element. Conclusions.— The International Collaboration on Cancer Reporting has published freely available, evidence-based data sets for gastric cancer reporting. Standardized reporting has been shown to improve patient care and facilitates data exchange and analysis for quality assurance, cancer epidemiology, and clinical and basic research.

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Section: Tumor Regressionmentioning

confidence: 99%

Data Set for Reporting Carcinoma of the Stomach in Gastrectomy

Shi

Badgwell

Grabsch

et al. 2021

Archives of Pathology &Amp; Laboratory Medicine

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Textbook outcome following oesophagectomy for cancer: international cohort study

Hodson¹,

Alderson²,

Bundred³

et al. 2022

British Journal of Surgery

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Background Textbook outcome has been proposed as a tool for the assessment of oncological surgical care. However, an international assessment in patients undergoing oesophagectomy for oesophageal cancer has not been reported. This study aimed to assess textbook outcome in an international setting. Methods Patients undergoing curative resection for oesophageal cancer were identified from the international Oesophagogastric Anastomosis Audit (OGAA) from April 2018 to December 2018. Textbook outcome was defined as the percentage of patients who underwent a complete tumour resection with at least 15 lymph nodes in the resected specimen and an uneventful postoperative course, without hospital readmission. A multivariable binary logistic regression model was used to identify factors independently associated with textbook outcome, and results are presented as odds ratio (OR) and 95 per cent confidence intervals (95 per cent c.i.). Results Of 2159 patients with oesophageal cancer, 39.7 per cent achieved a textbook outcome. The outcome parameter ‘no major postoperative complication’ had the greatest negative impact on a textbook outcome for patients with oesophageal cancer, compared to other textbook outcome parameters. Multivariable analysis identified male gender and increasing Charlson comorbidity index with a significantly lower likelihood of textbook outcome. Presence of 24-hour on-call rota for oesophageal surgeons (OR 2.05, 95 per cent c.i. 1.30 to 3.22; P = 0.002) and radiology (OR 1.54, 95 per cent c.i. 1.05 to 2.24; P = 0.027), total minimally invasive oesophagectomies (OR 1.63, 95 per cent c.i. 1.27 to 2.08; P < 0.001), and chest anastomosis above azygous (OR 2.17, 95 per cent c.i. 1.58 to 2.98; P < 0.001) were independently associated with a significantly increased likelihood of textbook outcome. Conclusion Textbook outcome is achieved in less than 40 per cent of patients having oesophagectomy for cancer. Improvements in centralization, hospital resources, access to minimal access surgery, and adoption of newer techniques for improving lymph node yield could improve textbook outcome.

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Fat clearance of upper gastrointestinal resection specimens increases lymph node yield and may result in nodal upstaging

Cited by 2 publications

References 9 publications

Data Set for Reporting Carcinoma of the Stomach in Gastrectomy

Data Set for Reporting Carcinoma of the Stomach in Gastrectomy

Textbook outcome following oesophagectomy for cancer: international cohort study

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