2013
DOI: 10.2337/dc12-2465
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Fasting Plasma Glucose at 24–28 Weeks to Screen for Gestational Diabetes Mellitus

Abstract: OBJECTIVETo evaluate the usefulness of a fasting plasma glucose (FPG) at 24–28 weeks’ gestation to screen for gestational diabetes mellitus (GDM).RESEARCH DESIGN AND METHODSThe medical records and results of a 75-g 2-h oral glucose tolerance test (OGTT) of 24,854 pregnant women without known pre-GDM attending prenatal clinics in 15 hospitals in China were examined.RESULTSFPG cutoff value of 5.1 mmol/L identified 3,149 (12.1%) pregnant women with GDM. FPG cutoff value of 4.4 mmol/L ruled out GDM in 15,369 (38.2… Show more

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Cited by 85 publications
(63 citation statements)
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References 9 publications
(5 reference statements)
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“…The positive predictive value was 0.322, and the negative predictive value was 0.928. 13 In our present study FPG cut off value of 5.1mmol/L identified 48 (11.5 %) pregnant women with GDM. The positive predictive value is 0.289, and the negative predictive value is 0.958 and is similar to the study by Zhu et al 13 Women with FPG values between 4.4 and 5.1mmol/L require a 75-g 2-h OGTT to confirm or rule out GDM.…”
Section: Discussionsupporting
confidence: 51%
See 1 more Smart Citation
“…The positive predictive value was 0.322, and the negative predictive value was 0.928. 13 In our present study FPG cut off value of 5.1mmol/L identified 48 (11.5 %) pregnant women with GDM. The positive predictive value is 0.289, and the negative predictive value is 0.958 and is similar to the study by Zhu et al 13 Women with FPG values between 4.4 and 5.1mmol/L require a 75-g 2-h OGTT to confirm or rule out GDM.…”
Section: Discussionsupporting
confidence: 51%
“…13 In their study FPG cut off value of 5.1 mmol/L identified 12.1% pregnant women with GDM. FPG cut off value of 4.4 mmol/L ruled out GDM in 38.2% women.…”
Section: Discussionmentioning
confidence: 94%
“…An FPG result ≤4.4 mmol/l has been associated with low risk and suggested as a potential screening test in the IADPSG recommendations [7]. A high negative predictive value of this screening test has been described in Middle Eastern and Chinese populations, but has not been addressed in European pregnant women [45,46]. Other screening strategies using the new WHO diagnostic criteria, such as a twostep screening strategy with a 50 g GCT followed by a 75 g OGTT if the GCT is abnormal, or selective screening according to risk factors, should also be evaluated prospectively in European populations.…”
Section: Risk Factors For Diabetes and Gdm • Previous Gestational Diamentioning
confidence: 99%
“…Our approach was similar to that of several studies designed with the aim to identify the best diagnostic approach for GDM (19,20,21,22,23). In the European countries, the nonconformity of screening and diagnostic procedures for GDM is responsible for the different reported prevalence rates of GDM (6).…”
Section: Discussionmentioning
confidence: 80%