Fasting Increases the Severity of Acute Pancreatitis in a Mouse Model: Implications for Preoperative Interventions to Reduce Complications of Pancreatic Surgery
Maria L SOUZA,
Suely ARIGA,
Denise F BARBEIRO
et al.
Abstract:Background: Acute pancreatitis following surgical or endoscopic procedures on the pancreas can compromise the outcome and lead to severe complications and even death. The aim of this study was to determine whether prolonged fasting affects the severity of acute pancreatitis (AP). Methods: Male mice were divided into 4 groups: Group CF (n=5) control animals that fasted for 24 hours; Group CNF (n=5) control animals that did not fast; Group APF (n=7) that fasted for 24 hours and underwent induction of acute panc… Show more
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