Fast selective black blood MR imaging.

Edelman, Robert R.; Chien, Daisy; Kim, Ducksoo

doi:10.1148/radiology.181.3.1947077

Cited by 358 publications

(234 citation statements)

References 11 publications

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“…Here, in one of the first studies to assess the measurement capabilities of MRI in the carotid artery at 3T, we demonstrated the high reproducibility of vessel wall area measurements using a dual-inversion segmented k-space GRE imaging technique. Table 4 Means, SDs, Intra-and Interobserver MAD and MRE for all Endpoints Black-blood techniques are commonly used to achieve flow suppression, even though they require a relatively long acquisition duration (32). The technique uses a nonselective inversion RF pulse that inverts the longitudinal magnetization of the entire volume in the transmit coil.…”

Section: Discussionmentioning

confidence: 99%

Assessment of the carotid artery by MRI at 3T: A study on reproducibility

Dehnavi

Doornbos

Tamsma

et al. 2007

Magnetic Resonance Imaging

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Purpose:To examine the reproducibility of carotid artery dimension measurements using 3T MRI. Materials and Methods:Ten healthy volunteers underwent three scans on two occasions for assessment of total vessel wall area (TVWA), total luminal area (TLA), and minimum (MinT) and maximum (MaxT) vessel wall thickness. A double inversion-recovery (IR) fast gradient-echo (FGRE) sequence was used on a commercial 3T system. During the first visit the subjects were scanned twice. The third scan was performed at least four days later. One observer traced all scans, and a second observer retraced the first scan series. Conclusion:With the use of a commercial 3T MR system, TVWA, TLA, and wall thickness measurements of the carotid artery can be assessed with good reproducibility.

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Section: Discussionmentioning

confidence: 99%

Assessment of the carotid artery by MRI at 3T: A study on reproducibility

Dehnavi

Doornbos

Tamsma

et al. 2007

Magnetic Resonance Imaging

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“…2a. A turbo spin-echo pulse sequence (turbo factor 17) preceded by a double-inversion preparation phase [6] was used. The field of view was 18 cm x 18 cm with a matrix size of 256 x 256, yielding an in-plane resolution of 0.70 mm x 0.70 mm pixel size.…”

Section: Methodsmentioning

confidence: 99%

High-Resolution Black-Blood MRI of the Carotid Vessel Wall Using Phased-Array Coils at 1.5 and 3 Tesla1

et al. 2005

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Purpose-To investigate the magnetic field dependence of the signal-to-noise ratio (SNR) for carotid vessel wall magnetic resonance imaging (MRI) using phased-array (PA) surface coils by comparing images obtained at 1.5 T and 3 T, and to determine to what extent the improved SNR at the higher field can be traded for improved spatial resolution.Materials and methods-Two pairs of dual-element PA coils were constructed for operation at the two field strengths. The individual elements of each PA were matched to 50 Ω impedance on the neck and tuned at the respective frequencies. The coils were evaluated on a cylindrical phantom positioned with its axis parallel to the main field, and with the coils placed on either side of the phantom parallel to the sagittal plane. In-vivo MR images of the carotid arteries were obtained in five subjects at both field strengths with a fast spin-echo double-inversion black-blood pulse sequence with fat saturation. SNR was measured at both field strengths using standard techniques.Results-At a depth corresponding to the average location of the carotid arteries in the study subjects, mean phantom SNR for the two coils was higher at 3 T by a factor of 2.5. The greater than linear increase is due to only partial coil loading of these relatively small coils. The practically achievable average SNR gain in vivo was 2.1. The lower in vivo SNR gain is attributed to a reduction in T 2 and prolongation of T 1 at the higher field strength and, to a lesser extent, the requirement for reduced refocusing pulse flip angle to operate within specific absorption ratio limits. The superior SNR at 3 T appears to provide considerably improved vessel wall delineation.Conclusions-Carotid artery vessel wall MRI using phased-array surface coils provides a considerable increase in SNR when field strength is raised from 1.5 T to 3 T. This increase can be traded for enhanced in-plane resolution.

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“…Black-blood imaging methods (9)(10)(11)(12)(13)(14), wherein blood signals are selectively suppressed using spatial presaturation (9,10), double inversion recovery (11,12), or motion-sensitizing magnetization preparation (13,14), if successfully combined with CE 3D MP-RAGE, may have the potential to provide an excellent differentiation between blood and tumors. However, it is challenging to achieve CE black-blood imaging due to a rapid recovery of blood signals along the echo train in MP-RAGE.…”

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confidence: 99%

Contrast-enhanced, three-dimensional, whole-brain, black-blood imaging: Application to small brain metastases

Park

Kim

2010

Magn. Reson. Med.

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Contrast-enhanced three-dimensional T 1 -weighted imaging based on magnetization-prepared rapid-gradient recalled echo is widely used for detecting small brain metastases. However, since contrast materials remain in both blood and the tumor parenchyma and thus increase the signal intensity of both regions, it is often challenging to distinguish brain tumors from blood. In this work, we develop a T 1 -weighted, black-blood version of single-slab three-dimensional turbo/ fast spin echo whole-brain imaging, in which the signal intensity of the brain tumor is selectively enhanced while that of blood is suppressed. For blood suppression, variable refocusing flip angles with flow-sensitizing gradients are employed. To avoid a signal loss resulting from the flow-sensitizing scheme, the first refocusing flip angle is forced to 180°. Composite restore pulses at the end of refocusing pulse train are applied to achieve partial inversion recovery for the T 1 -weighted contrast. Simulations and in vivo volunteer and patient experiments are performed, demonstrating that this approach is highly efficient in detecting small brain metastases. Magn Reson Med 63:553-561, 2010. V C 2010 Wiley-Liss, Inc.Key words: contrast-enhanced; metastatic tumor; black blood; magnetic resonance imaging; MRI; three dimensional; variable flip angle In brain metastasis, wherein blood vessels do not maintain the blood-brain barrier, exogenously administered small-molecular-weight contrast agents typically accumulate within the extravascular extracellular space. Thus, contrast-enhanced (CE) imaging methods (1-6), which are sensitive to the T 1 -shortening effect of contrast materials, have been used for the detection of brain metastases. Among them, CE T 1 -weighted two-dimensional spin echo (SE) imaging has gained widespread clinical acceptance for the detection of brain tumors with permeable vessels, providing high signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), but has limitations in detecting the small size of metastases due to partial-volume effects. To overcome this problem, magnetizationprepared rapid-gradient-echo (MP-RAGE) imaging (7,8), which is the most widely used three-dimensional (3D) T 1 -weighted imaging sequence, can be used to acquire high-resolution, isotropic whole-brain data in a clinically acceptable imaging time. Despite these advantages, a potential confound is the distribution of contrast agents within blood vessels and the tumor parenchyma resulting in the simultaneous enhancement of both regions, thereby impairing the accuracy of metastatic lesion detection. Thus, since the blood vessels close to the brain tumors may result in diagnostic confusion, it is necessary to selectively enhance the signal intensity of the brain tumors while suppressing the blood vessels elsewhere in the brain.Black-blood imaging methods (9-14), wherein blood signals are selectively suppressed using spatial presaturation (9,10), double inversion recovery (11,12), or motion-sensitizing magnetization preparation (13,14), if successfully...

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Fast selective black blood MR imaging.

Cited by 358 publications

References 11 publications

Assessment of the carotid artery by MRI at 3T: A study on reproducibility

Assessment of the carotid artery by MRI at 3T: A study on reproducibility

High-Resolution Black-Blood MRI of the Carotid Vessel Wall Using Phased-Array Coils at 1.5 and 3 Tesla1

Contrast-enhanced, three-dimensional, whole-brain, black-blood imaging: Application to small brain metastases

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