Fast Colorimetric Evaluation of Optimum Conditions for the Synthesis of Fluorescent Molecular Probes: Application to Neuronal TracersN,N-((Dialkylamino)styryl)-N-alkylpyridinium Salts

Abstract

The present communication reports the detection of new phosphorus-containing semilabile ligands for the Heck coupling reaction. We have developed a new screening methodology based on the batochrome properties of the cross-conjugated target molecules to rapidly test a large diversity of metal/ligand complexes for this coupling reaction.

A ferroelectric inorganic–organic hybrid based on NLO-phore stilbazolium

“…Generally, this increased stability of stilbazolium complexes could be attributed to the increased transparency of them which is caused by a profound blue-shift of the absorption transitions after the alkylation reaction. 20 However, the solid state absorption characterization of 1 and DAST (Fig. 7) show similar intensity of absorption at 1064 and 532 nm, and no significant absorption-shift after DAMS + in situ derivated to TAMS 2+ .…”

Combinatorial and High-Throughput Development of Sensing Materials: The First 10 Years

“…Additional practical challenges may occur from difficulties in the synthesis of those best reagent structures predicted from computations. Thus, combinatorial synthetic approaches have been applied for the development of new fluorescent − and colorimetric − reagents. Recent reviews are available on the fluorescent labels and probes. , Recent developments resulted in the discovery of a wide variety of new useful reagents for the detection of metal ions, ,,, ATP, GTP, dipeptides, tripeptides, and reagents that selectively bind to amyloid 332 and different cell components. , …”

“…Additional practical challenges may occur from difficulties in the synthesis of those best reagent structures predicted from computations. Thus, combinatorial synthetic approaches have been applied for the development of new fluorescent [329][330][331][332][333][334][335] and colorimetric [336][337][338][339] reagents. Recent reviews are available on the fluorescent labels and probes.…”

Encapsulation of Pd(OAc)2 catalyst in an ionic liquid phase confined in silica gels. Application to Heck–Mizoroki reaction

“…The coupling product is of interest as a labeling molecule in biology and it is important to be able to synthesize it without any metal traces. 40…”