2011
DOI: 10.1016/j.chroma.2011.09.069
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Fast chromatographic separation for the quantitation of the main flavone dyes in Reseda luteola (weld)

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Cited by 20 publications
(15 citation statements)
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“…Moreover, the levels of the antioxidant molecule, glutathione, and the activity of the antioxidant enzymes, superoxide dismutase, were elevated as compared to doxorubicin treatment alone. These findings confirmed the antioxidant potential of OA extract in MCF-7 cells that could be attributed to the presence of major flavonoids such as kaempferol, quercetin, isorhamnetin and luteolin (Barakat et al, 1991, Cristea et al, 2003, Moiteiro et al, 2008, Marques et al, 2009, Berrehal et al, 2010, Villela et al, 2011). The majority of natural antioxidants are polyphenols including flavonoids, which exhibit strong antioxidant activity by acting as free radical scavengers, hydrogen donors, singlet oxygen quenchers, and metal ion chelators, in addition to inducing gene expressions of antioxidant enzymes (Krinsky, 1992, Rice-Evans, 2001).…”
Section: Resultssupporting
confidence: 78%
See 1 more Smart Citation
“…Moreover, the levels of the antioxidant molecule, glutathione, and the activity of the antioxidant enzymes, superoxide dismutase, were elevated as compared to doxorubicin treatment alone. These findings confirmed the antioxidant potential of OA extract in MCF-7 cells that could be attributed to the presence of major flavonoids such as kaempferol, quercetin, isorhamnetin and luteolin (Barakat et al, 1991, Cristea et al, 2003, Moiteiro et al, 2008, Marques et al, 2009, Berrehal et al, 2010, Villela et al, 2011). The majority of natural antioxidants are polyphenols including flavonoids, which exhibit strong antioxidant activity by acting as free radical scavengers, hydrogen donors, singlet oxygen quenchers, and metal ion chelators, in addition to inducing gene expressions of antioxidant enzymes (Krinsky, 1992, Rice-Evans, 2001).…”
Section: Resultssupporting
confidence: 78%
“…Earlier phytochemical investigations on the members of Resedaceae such as Caylusea , Reseda and Ochradenus reveals kaempferol, quercetin, isorhamnetin and luteolin as a major flavonoid glycosides (Barakat et al, 1991, Cristea et al, 2003, Moiteiro et al, 2008, Marques et al, 2009, Berrehal et al, 2010, Villela et al, 2011). The use of extracts of members of the genus Ochradenus in folk medicine (Nawash and Al-Horani, 2011), antibacterial (Abutbul et al, 2005), antimalarial (Sathiyamoorthy et al, 1999) and anticancer activity (Thoppil et al, 2013) has previously been reported.…”
Section: Introductionmentioning
confidence: 99%
“…These values equalled or improved upon the values published for luteolin (1), genistein (2) and apigenin (3) in other UPLC/UHPLC studies. 16,18 3.1.2 UPLC-MS study. Previous studies have shown that mass spectrometric analysis of avonoid and isoavonoid dyes may be achieved effectively using electrospray ionisation (ESI) mass spectrometry in negative mode, 3,[19][20][21] and have allowed the characterisation of several fragmentation mechanisms using secondary and tertiary mass spectrometry ion fragmentation (MS 2 and MS 3 ).…”
Section: Resultsmentioning
confidence: 99%
“…Samples from the dyeing and rinsing baths were combined, filtered and analysed by HPLC, according to methods described earlier by Derksen et al [23] and Villela et al [24]. Instead, dyeing was performed in a laboratory reflux set-up in a 250 ml round-bottomed flask, allowing visual inspection of the dyeing process.…”
Section: Dyeing Proceduresmentioning
confidence: 99%