Fast and high-resolution MRI on the basis of interleaved-spiral technique at 4.7 T and its application for imaging of ischemic rat brain

Abstract

The interleaved-spiral magnetic resonance imaging (MRI) technique was implemented and optimized on a Bruker Biospec 47/30 scanner. The method gives rise to high-resolution images with a time saving factor of up to 8, as compared to the conventional approaeh. A multifunctional pulse sequence for the fast interleaved-spiral MRI was composed. These functions include spin intensity imaging, transverse relaxation time T 2 and apparent diffusion-weighted imaging. The method was used to obtain the dynamic resp0nses of a rat brain during ischemia.

Gridding and fast Fourier transformation on non-uniformly sparse sampled multidimensional NMR data

“…To verify the feasibility and speed advantage of the GFFT, conventional 3D HNCO experiment and its indirect dimensional spiral sampling version [35,47] were performed. The sample was a 1 mM aqueous solution (10% D 2 O) of uniformly 13 C and 15 N labeled ubiquitin.…”