Fast and accurate modeling and design of antibody-antigen complex using tFold
Fandi Wu,
Yu Zhao,
Jiaxiang Wu
et al.
Abstract:Accurate prediction of antibody-antigen complex structures holds significant potential for advancing biomedical research and the design of therapeutic antibodies. Currently, structure prediction for protein monomers has achieved considerable success, and promising progress has been made in extending this achievement to the prediction of protein complexes. However, despite these advancements, fast and accurate prediction of antibody-antigen complex structures remains a challenging and unresolved issue. Existing… Show more
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