Fast Analysis and Validation of Rutin in Anti-Psoriatic Ayurvedic Formulation by HPLC

Musthaba, S. Mohamed; Athar, M. T.; Kamal, YT; Baboota, Sanjula; Ali, Javed; Ahmad, Sayeed

doi:10.1080/10826076.2011.555687

Cited by 12 publications

(6 citation statements)

References 10 publications

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“…These components included in the majority phenolics from the benzoic compound group [ 244 ]. The antipsoriatic action is presented by many herbal mixtures, e.g., the combination of leaves of Wrightia tinctoria and Cocos nucifera oil rich in flavanoids, glycoflavones-iso-orientin, and phenolic acids [ 245 , 246 ] or the mixture of herbs used in Chinese medicine PSORI-CM01, which contains organic acids, phenolic acids, flavonoids, and terpenoids [ 247 ]. Another Chinese herbal medicine used for many years in the treatment of psoriasis is based on the plant Scutellaria baicalensis .…”

Section: Skin Diseasesmentioning

confidence: 99%

The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders

Działo

Mierziak

Korzun

et al. 2016

IJMS

495

316

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Phenolic compounds constitute a group of secondary metabolites which have important functions in plants. Besides the beneficial effects on the plant host, phenolic metabolites (polyphenols) exhibit a series of biological properties that influence the human in a health-promoting manner. Evidence suggests that people can benefit from plant phenolics obtained either by the diet or through skin application, because they can alleviate symptoms and inhibit the development of various skin disorders. Due to their natural origin and low toxicity, phenolic compounds are a promising tool in eliminating the causes and effects of skin aging, skin diseases, and skin damage, including wounds and burns. Polyphenols also act protectively and help prevent or attenuate the progression of certain skin disorders, both embarrassing minor problems (e.g., wrinkles, acne) or serious, potentially life-threatening diseases such as cancer. This paper reviews the latest reports on the potential therapy of skin disorders through treatment with phenolic compounds, considering mostly a single specific compound or a combination of compounds in a plant extract.

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Section: Skin Diseasesmentioning

confidence: 99%

The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders

Działo

Mierziak

Korzun

et al. 2016

IJMS

495

316

View full text Add to dashboard Cite

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“…The developed HPLC method is useful for the qualitative and quantitative estimation of rutin in 777 Oil and other products of traditional systems of medicine. [ 44 ]…”

Section: Introductionmentioning

confidence: 99%

A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: Adulterant of kurchi

Srivastava¹

2014

Phcog Rev

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Wrightia tinctoria R. Br. belongs to family Apocynaceae commonly called as Sweet Indrajao, Pala Indigo Plant, Dyer's Oleander. “Jaundice curative tree” in south India. Sweet Indrajao is a small, deciduous tree with a light gray, scaly smooth bark. Native to India and Burma, Wrightia is named after a Scottish physician and botanist William Wright (1740-1827). Sweet Indrajao is called dhudi (Hindi) because of its preservative nature. The juice of the tender leaves is used efficaciously in jaundice. Crushed fresh leaves when filled in the cavity of decayed tooth relieve toothache. In Siddha system of medicine, it is used for psoriasis and other skin diseases. Oil 777 prepared out of the fresh leaves of the plant has been assigned to analgesic, anti-inflammatory, and anti-pyretic activities and to be effective in the treatment of psoriasis. The plant is reported to contain presence of flavanoid, glycoflavones-iso-orientin, and phenolic acids. The various chemical constituents isolated from various parts of the plant are reported as 3,4-Seco-lup-20 (29)-en-3-oic acid, lupeol, stigmasterol and campetosterol, Indigotin, indirubin, tryptanthrin, isatin, anthranillate and rutin Triacontanol, Wrightial, cycloartenone, cycloeucalenol, β-amyrin, Alpha-Amyrin, and β-sitosterol, 14α-methylzymosterol. Four uncommon sterols, desmosterol, clerosterol, 24-methylene-25-methylcholesterol, and 24-dehydropollinastanol, were isolated and identified in addition to several more common phytosterols. The Triterpinoids components of the leaves and pods of Wrightia tinctoria also isolated. This article intends to provide an overview of the chemical constituents present in various parts of the plants and their pharmacological actions and pharmacognostical evaluation.

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“…Method of Mustabha et al (2011) and Habib et al (2016) was employed with minor modifications for carrying our rutin analysis by RP-HPLC.…”

Section: Rutin Analysis By Hplcmentioning

confidence: 99%

Use of Diaion HP20 Resin to Achieve High Rutin Containing Moringa oleifera Extract: Its Solubility and Anti-Bacterial Properties and Possible Applications in Nebulizer Formulation for COVID Patients

Palghadmal¹,

Bhosale²,

Kulkarni³

et al. 2022

GJHS

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Rutin with several pharmacological properties has been reported to be an effective inhibitor for SARS-COV-2 viral protease. Due to lack of specific drugs available for treatment of covid infection, hunt is on for possible herbal supplements that will impact multiplication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and also provide immunity to people against such infections. We report a simple and cost-effective method for extraction of rutin from Moringa oleifera, a plant with high nutritive value due to its rich contents in minerals, vitamins and other essential phytochemicals. The solubility of rutin in water was achieved using rutin-arginine mixture (identified as a good water-soluble version of rutin) and tested for its antibacterial activity against Klebsiella pneumoniae and E. coli by MIC studies and compared with rutin solubilized in methanol. Our results demonstrate easy scale of the rutin extraction process and such a process could be applicable to extraction of rutin from other medicinal plants as well. We demonstrate that rutin purified through column chromatography has 20% higher solubility in water and maintains its anti-bacterial properties against Klebsiella pneumoniae and E. coli. Our findings reveal new possibilities of using resin column chromatography for concentrating rutin from plant extracts. Also, potential use of water soluble rutin is envisaged for development of nebulizers for treatment of asthma, hyperglycemia, and pneumonia, seen in COVID-19 affected patients.

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Fast Analysis and Validation of Rutin in Anti-Psoriatic Ayurvedic Formulation by HPLC

Cited by 12 publications

References 10 publications

The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders

The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders

A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: Adulterant of kurchi

Use of Diaion HP20 Resin to Achieve High Rutin Containing Moringa oleifera Extract: Its Solubility and Anti-Bacterial Properties and Possible Applications in Nebulizer Formulation for COVID Patients

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