Fashionable But Debilitating Diseases: Tuberculosis Past and Present

Roberts, Charlotte A.

doi:10.1007/978-3-030-32181-9_2

Cited by 6 publications

(2 citation statements)

References 57 publications

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“…Tuberculosis (TB) stands as a prominent cause of mortality globally, particularly in the developing nations of sub-Saharan Africa, with Nigeria serving as a notable example [7] . Its impact has persisted throughout history, affecting up to one-third of the world's population, with the lifetime risk of contracting the disease potentially exceeding 10% [8] . This enduring presence has rendered TB a global pandemic, exerting a significant negative influence on the growth and development of nations 5 .…”

Section: Introduction Backgroundmentioning

confidence: 99%

Statistical overview on tuberculosis in Nigeria: Epidemiological insights and public health implications

OO,

BA,

et al. 2024

Int. J. Adv. Community Med.

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Tuberculosis (TB) remains a significant public health challenge in Nigeria, with high morbidity and mortality rates. This statistical overview provides insights into the epidemiology of TB in Nigeria, highlighting regional disparities, demographic factors, and key public health implications. Drawing from referenced studies and World Health Organization reports, the analysis reveals Nigeria's classification as a high TB burden country, with an estimated 460,000 new cases reported annually. The prevalence of TB stands at 616 cases per 100,000 population, with notable regional variations observed across different geographical zones. The findings emphasize the need for multifaceted approaches to TB control, including enhanced surveillance, improved diagnostics, and targeted interventions addressing social determinants of health. By understanding the complex epidemiological landscape of TB in Nigeria, policymakers and public health officials can formulate evidence-based strategies to mitigate disease burden and improve health outcomes for affected populations.

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Section: Introduction Backgroundmentioning

confidence: 99%

Statistical overview on tuberculosis in Nigeria: Epidemiological insights and public health implications

OO,

BA,

et al. 2024

Int. J. Adv. Community Med.

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“…The relatively high incidence, the appearing rifampicin-and multidrugresistant TB (MDR-TB) strains and the co-infection cases (especially with HIV) highlight the necessity of extensive TB research. This disease is mainly remembered due to its devastating effects during the 18th -19th century, when it was highly spread in Europe, implying an extraordinary burden (Bello et al 1999;Vuorinen 1999, Glaziou et al 2018Loddenkemper et al 2018;Roberts 2020), but has been a recognised threat for thousands of years (Gutierrez et al 2005;Daniel 2006;Baker et al 2015; Barberies et Váradi et al al. 2017).…”

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confidence: 99%

Lipid biomarker-based verification of TB infection in mother’s and daughter’s mummified human remains (Vác Mummy Collection, 18th century, CE, Hungary)

et al. 2021

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The perpetual burden of tuberculosis (TB) keeps drawing the focus of research on this disease. Among other risk factors (e.g., poor living conditions, malnutrition, smoking, HIV infection, etc.), being in close contact with a TB infected person requires special attention. For a better understanding of the disease, paleopathological investigations concerning TB have been carried out with various techniques for a long a time; nevertheless, analysis of incidence among family members is hardly possible in past populations. An exceptional group of naturally mummified individuals, the collection of the Vác mummies (Hungary, 18th century CE), is known about the large TB incidence rate, which has been revealed by aDNA analysis. Besides the high rate of TB infection, another interesting aspect of the collection is that in some cases, the family connections could be reconstructed. In this paper, we present the mycocerosic acid profiles gained by HPLC-HESI-MS measurements of two Vác mummies, who were mother and daughter according to the personal records. Earlier metagenomic analysis already revealed mixed M. tuberculosis infection with the same bacterial strains in both individuals; moreover, the same bacterial strains were recorded in both cases.

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Probable cases of tuberculosis in Early Medieval pastoralists of Eastern Europe

Buzhilova

2023

Tuberculosis

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Fashionable But Debilitating Diseases: Tuberculosis Past and Present

Cited by 6 publications

References 57 publications

Statistical overview on tuberculosis in Nigeria: Epidemiological insights and public health implications

Statistical overview on tuberculosis in Nigeria: Epidemiological insights and public health implications

Lipid biomarker-based verification of TB infection in mother’s and daughter’s mummified human remains (Vác Mummy Collection, 18th century, CE, Hungary)

Probable cases of tuberculosis in Early Medieval pastoralists of Eastern Europe

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