Fasciite à éosinophiles survenue secondairement à une infection par Borrelia burgdorferi

Belot, Véronique; Mulleman, Denis; Perrinaud, A.; Abdallah-Lotf, M.; Machet, Marie‐Christine; Machet, L.

doi:10.1016/s0151-9638(07)91831-1

Cited by 18 publications

(3 citation statements)

References 24 publications

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“…The role of environmental factors has also been suspected in the context of EF, although no case-control study is available. In case reports, EF has been linked to infection with Borrelia species , 2 , 9 , 47 , 51 , 87 , 107 , 116 brucellosis, 90 chronic hepatitis C, 90 tertiary syphilis, 90 chemical exposure, 11 trichloroethylene, 52 insect bites, 79 , 90 irradiation, 109 and various pharmaceuticals, including simvastatin, 28 , 108 phenytoin, 18 atorvastatin, 31 fosinopril, 10 alpha-methyldopa, 90 subcutaneous heparin use, 20 and antituberculosis therapy. 104 Geographical clustering of scleroderma-like syndromes, including EF, was reported in a rural area in Italy.…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Severe Aplastic Anemia Associated With Eosinophilic Fasciitis

Masson

Bouaziz²,

Latour

et al. 2013

Medicine

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Diffuse eosinophilic fasciitis (Shulman disease) is a rare sclerodermiform syndrome that, in most cases, resolves spontaneously or after corticosteroid therapy. It has been associated with hematologic disorders, such as aplastic anemia. The clinical features and long-term outcomes of patients with eosinophilic fasciitis and associated aplastic anemia have been poorly described. We report the cases of 4 patients with eosinophilic fasciitis and associated severe aplastic anemia. For 3 of these patients, aplastic anemia was refractory to conventional immunosuppressive therapy with antithymocyte globulin and cyclosporine. One of the patients received rituximab as a second-line therapy with significant efficacy for both the skin and hematologic symptoms. To our knowledge, this report is the first to describe rituximab used to treat eosinophilic fasciitis with associated aplastic anemia.In a literature review, we identified 19 additional cases of eosinophilic fasciitis and aplastic anemia. Compared to patients with isolated eosinophilic fasciitis, patients with eosinophilic fasciitis and associated aplastic anemia were more likely to be men (70%) and older (mean age, 56 yr; range, 18–71 yr). Corticosteroid-containing regimens improved skin symptoms in 5 (42%) of 12 cases but were ineffective in the treatment of associated aplastic anemia in all but 1 case. Aplastic anemia was profound in 13 cases (57%) and was the cause of death in 8 cases (35%). Only 5 patients (22%) achieved long-term remission (allogeneic hematopoietic stem cell transplantation: n = 2; cyclosporine-containing regimen: n = 2; high-dose corticosteroid-based regimen: n = 1).

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Section: Discussion and Literature Reviewmentioning

confidence: 99%

Severe Aplastic Anemia Associated With Eosinophilic Fasciitis

Masson

Bouaziz²,

Latour

et al. 2013

Medicine

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“…Familial cases have been reported although no specific HLA phenotype is associated with the disease [5][6][7][8]. There are also reports of EF associated with Mycoplasma and Borrelia infections and as a paraneoplastic phenomenon [9][10][11][12][13]. Other anecdotal disease associations have been reported [3,14,15].…”

Section: Introductionmentioning

confidence: 99%

Eosinophilic Fasciitis Treated with Tocilizumab: Demonstration of Efficacy after Withdrawal and Re-Challenge in a Patient

Thomson¹

2015

J Rheum Dis Treat

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“…The classical form is acrodermatitis chronica atrophicans, but infection with Borrelia spp. has also been related to morphoea (2), lichen sclerosus et atrophicus (3) and, rarely, eosinophilic fasciitis (EF) (4)(5)(6)(7). Diagnosis is mainly clinical, and a deep skin biopsy can reveal a typical lymphoplasmacytic infiltrate.…”

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confidence: 99%