Breeding is probably as old as agriculture itself. Early vegetable breeders developed landrace cultivars by selection of favorable variations in horticultural traits, yield and resistance to diseases and other problems. Later new breeding methods were developed, including hybridization techniques, culminating with the use of recently developed molecular tools, all leading to our modern improved vegetable cultivars. Great emphasis on protection of cultivars by seed companies, including development of F 1 hybrids, plant cultivar protection and patenting have been done. There were 392 vegetable crops cultivated worldwide but only slightly over one half of the total number of them have attracted commercial breeding attention. In recent times, there have been challenges and new trends in the breeding domain. These include an unrelenting movement away from well supported public breeding institutions to a breeding world dominated by private entities, and an increase in size of the companies in the private sector, with emphasis on the major vegetable crops.