Familially Accumulated Schizophrenia (Folie à Cinq) in Association with Stein-Leventhal Syndrome

Pethö, B; Karczag, I; Czeizel, A.

doi:10.1159/000283940

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…She suddenly became confused, excited, and walked around at night one day around ovulation. She was admitted to hospital, and [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50] mg/day of haloperidol was administered as treatment, but her excitation persisted. She said that she was being looked at by all people in the world.…”

Section: Casementioning

confidence: 99%

Elevated Serum LH and Androgens in Affective Disorder Related to the Menstrual Cycle: With Reference to Polycystic Ovary Syndrome

Matsunaga

Sarai

1993

Psychiatry Clin Neurosci

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The hypothalamo‐pituitary‐gonadal axis was studied in 12 young women with manic‐depressive or psychotic symptoms which obviously fluctuated in association with the menstrual cycle, and also in 36 psychiatric patients with other diagnoses. The hormonal features frequently observed among these 12 cases were elevated basal LH (8 of 12 cases), decreased basal FSH (6 of 12), elevated serum testosterone (6 of 12), androstenedione (5 of 12) and/or dehydroepiandrosterone‐sulfate (3 of 11). These abnormalities resemble those of polycystic ovary syndrome (PCOS). An ultrasonographical study revealed polycystic changes in 8 out of the 12 cases. In 10 cases clomiphene citrate was administered, and was effective in 8. In comparison with the pathophysiology of PCOS, a possible relationship was suggested between the psychiatric problems and the PCOS‐like hormonal abnormalities in these cases.

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Section: Casementioning

confidence: 99%

Elevated Serum LH and Androgens in Affective Disorder Related to the Menstrual Cycle: With Reference to Polycystic Ovary Syndrome

Matsunaga

Sarai

1993

Psychiatry Clin Neurosci

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“…Shared psychotic disorder is usually “Folie à deux” (delusions shared by two individuals) [ 1 , 2 ] or more rarely “Folie à trois” [ 3 ], while “Folie à quatre” and delusions shared by more than four individuals are extremely rare. Indeed, only a few cases of “Folie à quatre” [ 4 – 6 ] and “Folie à cinq” [ 7 , 8 ] have been reported. In recent years, we are aware of only one such case of “Folie à quatre” in Japan [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Genetic or Psychogenic? A Case Study of “Folie à Quatre” Including Twins

Ohnuma

Arai

2015

Case Reports in Psychiatry

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Shared psychotic disorder, characterized by shared delusion among two or more subjects (termed “Folie à deux,” “trois,” etc.), is often associated with strong religious beliefs or social isolation, factors creating strong psychological sympathy. Recently, we treated a rare familial case of “Folie à quatre” in central Tokyo without such influences. The proband was a schizophrenia patient and younger brother within monozygotic twins. Positive symptoms were “transmitted” to remaining family members, his elder brother, mother, and father father, in a relatively short period of three months. Although the pathophysiology of these positive symptoms (delusions and hallucinations) remains unclear, the transmission pattern suggests the primacy of social and environmental factors (and/or their interaction), while genetics appeared less influential in this “Folie à famille.” Although undiagnosed psychoses in the whole family cannot be excluded, they did not share the other negative schizophrenia symptoms of the proband. A strong familial connection appeared to be the most important factor for the common delusion and hallucination.

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“…By means of a health questionnaire study, Orenstein et al (1986) suggested an association between POD and Briquet's syndrome, and found that patients with POD report significantly more psychological and physical complaints than normal controls. Petho et al (1982) described a family in which paranoid schizophrenia was diagnosed in both parents and their three daughters. All the daughters suffered from POD.…”

Section: Introductionmentioning

confidence: 99%