Familial pheochromocytoma and islet cell tumor of the pancreas

Carney, J. Aidan; Go, Vay Liang W.; Gordon, Hymie; Northcutt, Robert C.; Pearse, A. G. E.; Sheps, Sheldon G.

doi:10.1016/0002-9343(80)90295-8

Cited by 58 publications

(13 citation statements)

References 17 publications

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“…Pheochromocytoma is not usually part of this complex; however, the occurrence of pheochromocytoma and pancreatic islet cell tumors has been reported in some families (Carney et al, 1980). Various crossover syndromes have been reported in which pheochromocytoma has been associated with characteristics of MEN1, MEN2A, MEN2B, von Recklinghausen's neurofibromatosis (NF), VHL and the ZollingerEllison syndrome (Cameron et al, 1978).…”

Section: Other Pheochromocytomasmentioning

confidence: 99%

Pheochromocytoma and Paraganglioma

Pacák

Wimalawansa

2015

Endocrine Practice

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Section: Other Pheochromocytomasmentioning

confidence: 99%

Pheochromocytoma and Paraganglioma

Pacák

Wimalawansa

2015

Endocrine Practice

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“…In addition, there are multiple reports in the literature of MEN1 and MEN2 overlapping with the coexistence of pancreatic islet cell tumors and pheochromocytoma [14][15][16]. Carney et al [17] described 3 unrelated families with 11 affected patients: 10 with pheochromocytoma, 4 islet cell tumors of the pancreas, and 3 with both. These tumors occurred in a manner consistent with autosomal dominant inheritance suggesting that pancreatic islet cell tumor, and pheochromocytoma is a genetically determined syndrome.…”

Section: E27mentioning

confidence: 99%

Wilms' tumor, pancreatic islet cell carcinoma, and pheochromocytoma in a child

Sola

Gutierrez

Thompson

et al. 2008

Journal of Pediatric Surgery

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“…In 1997, follow-up of the mother and daughter in the Carney et al report 12 disclosed that one of the daughter's 2 sons had multiple intracranial and intraspinal hemangioblastomas (a component of von Hippel-Lindau disease) and café-au-lait spots and a meningioma (both of which are findings common in neurofibromatosis). The second son had pheochromocytoma, a neoplasm that may complicate von Hippel-Lindau disease and also neurofibromatosis.…”

Section: Familial Multiple Endocrine Tumors and Other Associated Condmentioning

confidence: 99%

Familial Multiple Endocrine Neoplasia

2005

American Journal of Surgical Pathology

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In 1903, Erdheim described the case of an acromegalic patient with a pituitary adenoma and three enlarged parathyroid glands. Fifty years later, Underdahl et al reported 8 patients with a syndrome of pituitary, parathyroid, and pancreatic islet adenomas. In 1954, Wermer found that the syndrome was transmitted as a dominant trait. In 1959, Hazard et al described medullary (solid) thyroid carcinoma (MTC), a tumor that later was found to be a component of two endocrine syndromes. The first of these described by Sipple in 1961 comprised pheochromocytoma, MTC, and parathyroid adenoma. The second, described by Williams et al in 1966, was the combination of mucosal neuromas, pheochromocytoma, and MTC. In 1968, Steiner et al introduced the term "multiple endocrine neoplasia" (MEN) to describe disorders featuring combinations of endocrine tumors; they designated the Wermer syndrome as MEN 1 and the Sipple syndrome as MEN 2. In 1974, Sizemore et al concluded that the MEN 2 category included two groups of patients with MTC and pheochromocytoma: one with parathyroid disease and a normal appearance (MEN 2A) and the other without parathyroid disease but with mucosal neuromas and mesodermal abnormalities (MEN 2B). Later, additional nonendocrine conditions (von Recklinghausen neurofibromatosis and von Hippel-Lindau disease) were found accompanying other more recently described familial MEN syndromes, indicating that these diseases are very complicated disorders.

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Familial pheochromocytoma and islet cell tumor of the pancreas

Cited by 58 publications

References 17 publications

Pheochromocytoma and Paraganglioma

Pheochromocytoma and Paraganglioma

Wilms' tumor, pancreatic islet cell carcinoma, and pheochromocytoma in a child

Familial Multiple Endocrine Neoplasia

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