Familial dilated cardiomyopathy complicated by left ventricular aneurysm.

Abstract

SUMMARYTwo siblings presented with symptoms of left ventricular dysfunction and ventricular arrhythmias. Echocardiography and left ventriculography revealed dilatation, diffuse hypokinesis and apical aneurysm of the left ventricle in both cases. Myocardial infarction was unlikely by history and examinations. We diagnosed them as cases of familial dilated cardiomyopathy complicated by left ventricular aneurysm. Additional Indexing Words: Dilated cardiomyopathyLeft ventricular aneurysm ILATED cardiomyopathy with left ventricular aneurysm has been rarely reported,1),2) and there are no reports of familial occurrence of this association. We report herein two siblings with dilated cardiomyopathy complicated by left ventricular aneurysm. CASE REPORT Case 1:A 56-year-old man was admitted to our clinic because of the gradual onset of chest discomfort and dyspnea lasting for a few hours. He had been suffering from the symptoms for 14 years, but had no history of chest pain suggestive of ischemic heart disease or myocarditis.On admission, an electrocardiogram (ECG) showed sustained ventricular tachycardia. After electrical cardioversion, ECG showed Q waves in leads III, aVF, and V1-V3, diffuse ST-T abnormalities, complete left bundle branch block, and first-degree atrioventricular block (Fig. 1). Frequent,

Left ventricular aneurysm in patients with idiopathic dilated cardiomyopathy: clinical analysis of six cases

“…[12][13][14][15][16] In total, eight case reports were identified, but five were confirmed as familial dilated cardiomyopathy (FDCM), in whom all LVAs described were located at the LV apex. The remaining three patients were diagnosed with IDCM, and the LVA was located at the posterobasal wall in two patients, and the anterolateral wall in one patient.…”

Unusual Presentation of a Left Ventricular Aneurysm

“…[1][2][3][4][5][6] Congenital or idiopathic aneurysms of the left ventricle also have been observed. The resting electrocardiogram showed abnormal Q and T negative waves in leads II, III, and aVF.…”

“…(ECHOCARDIOGRAPHY, Volume 18, October 2001) aneurysm, ventricle, posterior, normal coronary artery A left ventricular aneurysm can be caused by a variety of factors: ischemic necrosis of the myocardium regardless of the underlying mechanism, myocarditis, dilated cardiomyopathy, sarcoidosis, syphilis, tuberculosis, AIDS, and thoracic trauma. [1][2][3][4][5][6] Congenital or idiopathic aneurysms of the left ventricle also have been observed. [7][8][9] Although a coronary lesion is generally the primary cause of a left ventricular aneurysm, 1,1 0,11 the literature does not describe any cases of ventricular aneurysm associated with normal coronary arteries with an etiology that was initially unknown and subsequently conrmed a years after an episode of ischemic disease.…”