Familial Colocalization of Lichen Planus and Vitiligo on Sun Exposed Areas

Abstract

Lichen planus and vitiligo are common skin disorders. Colocalization which is rarely reported may consider the koebner phenomenon related to the photo damage causing initiation of lichen planus over vitiliginous skin. We report a 37-year-old mother and her 23-year-old daughter, both farmers and known cases of vitiligo with subsequent gradual onset of pruritic skin lesions of lichen planus starting first over previous vitiliginous skin on sun exposed areas. Coexistence and colocalization of lichen planus and vitiligo in two members of a family is very rare and has not been reported previously according to our knowledge. Predominant colocalization was on vitiliginous areas which may explain actinic damage as a triggering factor for inducing lichen planus in long-standing vitiligo and supports its pathogenic relationship.

Frontal Fibrosing Alopecia and Vitiligo: Coexistence or True Association

“…Additionally, there are several reports describing lesions of LP that developed mainly over sun-exposed vitiliginous skin [25,26,29,30,31]. Extrapolating this to FFA, actinic damage in vitiliginous skin may trigger initiation of FFA on vitiligo-affected skin.…”

“…Lichen planus (LP) has been previously associated with vitiligo [23,24,25,26,27,28,29,30,31]. Furthermore, some authorities consider FFA as a variant of LPP [19,20].…”

Letters to the editors Vitiligo and lichen planus – common etiopathogenesis or coincidence?

“…Baghestani i wsp. [6] opisali współwystępowanie dermatoz u matki i cór-ki. Zaledwie jeden opis dotyczył okolic genitalnych (moszny) [7].…”

Lichen planus verrucosus in an association with vitiligo

“…In our case hyperkeratotic LP was associated with vitiligo. S. Baghestani et al have reported familial coexistence of LP and vitiligo, correspondingly, J. Wyte et ala case of long-standing vitiligo that was spared in LP [22,23]. G. Kravvas et al reviewed many theories of LP association with vitiligo as sun-exposed depigmented areas play an important part in the initiation of LP; the evident manifestation of the Koebner phenomenon in vitiligo area.…”