Familial brachioradial pruritus

Abstract

Spinal disease alone cannot explain the symptoms of brachioradial pruritus, which in our patients was characterized by symptom-free periods broken off by relapse late in the summer each year. The pedigree suggests this hereditary form of brachioradial pruritus to be dominant and possibly X-linked.

A case of neuropathic brachioradial pruritus caused by cervical disc herniation

“…In addition to idiopathic forms of BRP, as was seen in the patient presented here, a possible X-linked familial form of BRP has recently been described. 12 …”

Brachioradial pruritus as a result of cervical spine pathology: The results of a magnetic resonance tomography study

“…[1][2][3] For nearly 30 years, BRP was considered to be related to ultraviolet (UV) irradiation because UV exposure worsens the symptom. 2,[4][5][6][7][8][9][10][11][12][13][14] As early as 1983, Heyl 3 proposed that BRP may be caused by nerve injury in the cervical spine or by nerve compression (NC). Several recent studies have suggested that BRP may result from cervical spine lesions such as radiculopathy, disk herniation, osteophytes, or spinal neoplasms.…”

Neurophysiological assessment of brachioradial pruritus patients

“…However, the presence of high frequency of radicular involvement in ENMG in individuals without BRP suggests additional associated causes. In this sense, a hereditary cause was suggested by Wallengren and Dahlbäck, who reported BRP in several members of the same family 20 . Notwithstanding, genome wide association studies were not found in our late literature search.…”