Familial biatrial cardiac myxoma with glandular elements: A Rare entity with review of literature

Abstract

Cardiac myxomas are benign neoplasm of the heart with an incidence of 0.3%. Glandular cardiac myxomas are very rare and accounts for less than 3% of all cardiac myxomas. Here, we report a case of familial glandular cardiac myxoma in a 35 year old male who complained of exertional dyspneoa and weakness of right side of body on clinical presentation. Associated features of Carney's complex were not present. Family history revealed presence of cardiac myxoma in younger brother and sister. Transthoracic echocardiography detected biatrial myxoma. Excision of both lesions was done under cardiopulmonary bypass. Histopathology confirmed myxoma with glandular elements. Postoperative course was uneventful.

A giant left atrial myxoma transits across patent foramen ovale a PFO mimicking biatrial myxoma: a case report

“…Approximately 7% of cardiac myxomas are familial or occur as Carney syndrome. 4 This sporadic case was not considered Carney syndrome since no apparent evidence of skin, endocrine system, or other systemic abnormalities was found during the health check-up. Further magnetic resonance imaging (MRI) and genetic testing can confirm the diagnosis.…”

“…In contrast to solitary myxoma, familial or syndromic myxoma tumours tend to occur in younger individuals, are more frequently found in multiple locations, and have a higher likelihood of postoperative recurrences, which may reflect their multicentric nature. 4 The clinical presentation of cardiac myxoma varies depending on the location and size of the tumour. 4 While echocardiography can serve as the primary diagnostic method for asymptomatic patients, 2 cardiac MRI offers superior tissue discrimination.…”

“… 4 The clinical presentation of cardiac myxoma varies depending on the location and size of the tumour. 4 While echocardiography can serve as the primary diagnostic method for asymptomatic patients, 2 cardiac MRI offers superior tissue discrimination. 5 Surgical excision of myxomas is generally considered as curative.…”