Familial autoimmunity and risk of developing immune thrombocytopenia and Evans syndrome
Michell M. Lozano Chinga,
James B. Bussel,
Mark N. Fluchel
et al.
Abstract:BackgroundImmune thrombocytopenia (ITP) and Evans syndrome (ES) are manifestations of immune dysregulation. Genetic variants in immune‐related genes have been identified in patients with ITP and especially ES. We aimed to explore familial autoimmunity in patients with ITP and ES to understand possible contributions to chronicity.ProcedureWe assessed family history in two ways: via patient report for ITP and ES and by population‐based analysis using the Utah Population Database (UPDB) for ITP. A total of 266 pa… Show more
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