“Familial” apical ballooning syndrome (Takotsubo cardiomyopathy)

Kumar, Gautam; Holmes, David R.; Prasad, Abhiram

doi:10.1016/j.ijcard.2009.03.078

Cited by 76 publications

(43 citation statements)

References 5 publications

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“…Cardiac syndrome X also is most common in post-menopausal women, and endothelial dysfunction is thought to affect the underlying pathophysiology (75,76). A genetic component is suggested by the observation of takotsubo cardiomyopathy occurrence in 2 sisters and in a mother-daughter pair (77,78).…”

Section: Pathophysiologymentioning

confidence: 99%

Takotsubo Cardiomyopathy: A Unique Cardiomyopathy With Variable Ventricular Morphology

Hurst

Prasad

Askew

et al. 2010

JACC: Cardiovascular Imaging

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232

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Takotsubo cardiomyopathy is an important differential diagnosis of acute coronary syndrome. It is characterized by normal (or near-normal) coronary arteries, regional wall motion abnormalities that extend beyond a single coronary vascular bed, and often, a precipitating stressor. Variants of the classical left ventricular apical ballooning, including mid- or basal left ventricular wall motion abnormalities, are increasingly recognized. Takotsubo cardiomyopathy is not rare, and heightened awareness of this unique cardiomyopathy likely will lead to a higher reported incidence. Diagnosis of takotsubo cardiomyopathy has important implications for clinical management at presentation and afterward. The long-term prognosis is generally favorable; however, a small subset has potentially life-threatening complications during the initial presentation. The pathophysiologic mechanism is unknown, but catecholamine excess likely has a central role.

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Section: Pathophysiologymentioning

confidence: 99%

Takotsubo Cardiomyopathy: A Unique Cardiomyopathy With Variable Ventricular Morphology

Hurst

Prasad

Askew

et al. 2010

JACC: Cardiovascular Imaging

Self Cite

232

190

View full text Add to dashboard Cite

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“…Pison et al 4 have described the occurrence of this condition in two sisters. Kumar et al 5 have reported similar existence in a family involving mother and a daughter. In both incidences, the syndrome was precipitated by different stresses at different time periods.…”

Section: Discussionmentioning

confidence: 76%

Apical ballooning syndrome in first degree relatives

Subban

Ramachandran

Victor

et al. 2012

Indian Heart Journal

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Apical ballooning syndrome (Takotsubo cardiomyopathy) is an unusual stress-related reversible cardiomyopathy occurring commonly in postmenopausal females. Genetic etiology of this condition is uncertain. A 68-year-old female and her daughter aged 43 got admitted to our institute simultaneously with acute chest pain following demise of one of their close relative. Both had features typical of Takotsubo cardiomyopathy and recovered completely. This reports point to the possible genetic predisposition to this abnormality.

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“…[12] Possibility of a genetic predisposition may also exist. [13] There is emerging evidence of right ventricular affection in some cases. [14] Despite the severity of acute illness, stress induced cardiomyopathy is a transient disorder managed with supportive therapy.…”

Section: Discussionmentioning

confidence: 99%

Postoperative Takotsubo cardiomyopathy

2014

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Takotsubo cardiomyopathy also known as transient apical ballooning syndrome or stress induced reversible cardiomyopathy is an increasingly reported syndrome generally characterized by transient systolic dysfunction of the apical and/or mid segment of the left ventricle. It is frequently precipitated by severe stress and clinically mimics an acute ST-elevation myocardial infarction, with angiographically normal coronary arteries. A high index of suspicion is needed to diagnose this syndrome. We describe a patient who developed Takotsubo cardiomyopathy in the post-operative period following vaginal hysterectomy.

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“Familial” apical ballooning syndrome (Takotsubo cardiomyopathy)

Cited by 76 publications

References 5 publications

Takotsubo Cardiomyopathy: A Unique Cardiomyopathy With Variable Ventricular Morphology

Takotsubo Cardiomyopathy: A Unique Cardiomyopathy With Variable Ventricular Morphology

Apical ballooning syndrome in first degree relatives

Postoperative Takotsubo cardiomyopathy

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