Familial Aggregation of Non-Hodgkin's Lymphoma (NHL). A Case Report

Loves, Sandra; Haan, Lieuwe de; Daenen, Simon

doi:10.1186/1897-4287-4-3-136

Cited by 4 publications

(5 citation statements)

References 17 publications

(18 reference statements)

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“…Familial clustering of NHL has been described, including a report of 38 families with multiple cases of NHL [129]. A large case–control study (the Scandinavian Lymphoma Etiology [SCALE] study) undertaken in Denmark and Sweden found a history of hematopoietic disorders among any first-degree relatives to be a significant risk factor for all NHLs (odds ratio: 1.8; 95% CI: 1.2–2.5) [130].…”

Section: Genetic and Epigenetic Factors And Ocular Adnexal Nhlmentioning

confidence: 99%

Ocular adnexal non-Hodgkin’s lymphoma: a review of epidemiology and risk factors

Moslehi

Schymura

Nayak

et al. 2011

Expert Review of Ophthalmology

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Ocular adnexal non-Hodgkin’s lymphoma (NHL), the most common form of ophthalmic NHL, has a unique incidence pattern showing a steady and rapid increase in the past few decades, nearly equal rates among both genders, and predominance among Asians/Pacific Islanders. No major cause for ocular adnexal NHL has been identified, although infectious agents, immune disorders and genetic/epigenetic factors have all been implicated in its etiology. Identifying putative risk factors and biologic mechanisms leading to carcinogenesis in ocular adnexal NHL may enable implementation of effective preventive and/or therapeutic approaches for this malignancy. This article summarizes current knowledge on epidemiology of ocular adnexal NHL and the role of various potential risk factors in its etiology.

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Section: Genetic and Epigenetic Factors And Ocular Adnexal Nhlmentioning

confidence: 99%

Ocular adnexal non-Hodgkin’s lymphoma: a review of epidemiology and risk factors

Moslehi

Schymura

Nayak

et al. 2011

Expert Review of Ophthalmology

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“…In 2006, Loves et al. reported a family in which three male siblings developed NHL [ 6 ]. Those three siblings had different pathological types of lymphoma and were diagnosed at ages 45, 56, and 52 years.…”

Section: Discussionmentioning

confidence: 99%

“…In the literature review, we found multiple cases of siblings with NHL (some are as case reports and others included in crosssectional and other research studies). In 2006, Loves et al reported a family in which three male siblings developed NHL [6]. Those three siblings had different pathological Fig.…”

Section: Discussionmentioning

confidence: 99%

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Lymphoblastic lymphoma in two young siblings (coincidence or genetics?): two case reports

et al. 2021

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Background Non-Hodgkin lymphoma is the fourth most common malignancy in children, and it is not considered to be a hereditary disorder. However, it could affect members from the same family. Case presentation We are presenting two cases of Caucasian female siblings who were diagnosed with mediastinal lymphoblastic lymphoma in the same year. The two young females were presented to the emergency department with respiratory symptoms. After doing radiological investigations and biopsies, they were diagnosed with lymphoblastic lymphoma. The elder sister died before confirming the diagnosis, and the other is on chemotherapy now, with good treatment outcomes. Conclusions This case emphasizes the crucial role of precursor genetics in lymphoblastic lymphomas and suggests a strong relation between these genetics and age at symptom presentation. This is the first report of non-Hodgkin lymphoma in a pair of siblings in the pediatric population.

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“…In the literature review, we found multiple cases of siblings with NHL (some are as case reports and others included in cross-sectional and other research studies). In 2006 Loves et al reported a family in which three male siblings developed NHL (7). Those three siblings had different pathological types of lymphoma and were diagnosed at ages (45,56,52).…”

Section: Discussionmentioning

confidence: 99%

Lymphoblastic lymphoma in two young siblings (coincidence or genetics?): a case report

Hassan

Makhoul

Sallameh

et al. 2021

Preprint

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Background: Non-Hodgkin lymphoma is the fourth most common malignancy in children and it is not considered to be a hereditary disorder. However, it could affect members from the same family.Case presentation: We are presenting two cases of Caucasian female siblings who were diagnosed with mediastinal lymphoblastic lymphoma in the same year. The two young females were presented to the emergency department with respiratory symptoms. After doing radiological investigations and biopsies, the diagnosis of lymphoblastic lymphoma was done. The elder sister died before confirming the diagnosis, and the other one is on chemotherapy now and the treatment outcomes is good.Conclusions: This case emphasize the crucial role of precursor genetics in lymphoblastic lymphomas and suggesting the strong relation between those genetics and the age of symptoms presentation. This is the first report of non-Hodgkin siblings pair in the pediatric population.

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Familial Aggregation of Non-Hodgkin's Lymphoma (NHL). A Case Report

Cited by 4 publications

References 17 publications

Ocular adnexal non-Hodgkin’s lymphoma: a review of epidemiology and risk factors

Ocular adnexal non-Hodgkin’s lymphoma: a review of epidemiology and risk factors

Lymphoblastic lymphoma in two young siblings (coincidence or genetics?): two case reports

Lymphoblastic lymphoma in two young siblings (coincidence or genetics?): a case report

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