Familial aggregation of cluster headache

Cruz, Simão; Lemos, Carolina; Monteiro, José

doi:10.1590/0004-282x20130170

Cited by 11 publications

(14 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considerably rare, it has an estimated prevalence of approximately 1 in 1000, however its occurrence varies across geographical regions and has been reported to be as high as 1 in 500 [3][4][5][6][7][8]. Those with a family history of CH appear to have an increased risk of developing the condition [9][10][11][12] . Estimations of the presence of a positive family history amongst sufferers varies across studies.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of familial cluster headache: a systematic review and meta-analysis

O’Connor

Simpson

Houlden³

et al. 2020

J Headache Pain

View full text Add to dashboard Cite

Introduction: The population rate of familial cluster headache (CH) has been reported to be as high as 20% however this varies considerably across studies. To obtain a true estimate of family history in CH, we conducted a systematic review and meta-analysis of previously published data. Methods: Our systematic review involved a search of electronic databases (Medline, EMBASE, PubMed, CINAHL) to identify and appraise studies of interest utilising the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. To further ameliorate the accuracy of our analysis we included an additional unpublished cohort of CH patients recruited at a tertiary referral centre for headache, who underwent detailed family history with diagnostic verification in relatives. Data was extracted and meta-analysis conducted to provide a true estimation of family history. Results: In total, we identified 7 studies which fulfilled our inclusion criteria. The estimated true prevalence of CH patients with a positive family history was 6.27% (95% CI:4.65-8.40%) with an overall I 2 of 73%. Fitted models for gender subgroups showed higher estimates 9.26% (95% CI: 6.29-13.43%) in females. However the I 2 for the female model was 58.42% and significant (p = 0.047). Conclusion: Our findings estimate a rate of family history in CH to be approximately 6.27% (95% CI: 4.65-8.40%). While estimates were larger for female probands, we demonstrated high heterogeneity in this subgroup. These findings further support a genetic role in the aetiology of CH.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of familial cluster headache: a systematic review and meta-analysis

O’Connor

Simpson

Houlden³

et al. 2020

J Headache Pain

View full text Add to dashboard Cite

show abstract

“…Considerably rare, it has an estimated prevalence of approximately 1 in 1,000, however its occurrence varies across geographical regions and has been reported to be as high as 1 in 500 [3][4][5][6][7][8]. Those with a family history of CH appear to have an increased risk of developing the condition [9][10][11][12] . Estimations of the presence of a positive family history amongst sufferers varies across studies.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Familial Cluster Headache: A Systematic Review and Meta-Analysis

OConnor

Simpson

Houlden

et al. 2020

Preprint

View full text Add to dashboard Cite

Introduction: The population rate of familial cluster headache (CH) has been reported to be as high as 20%, however this varies considerably across studies. To obtain a true estimate of family history in CH, we conducted a systematic review and meta-analysis of previously published data. Methods: Our systematic review involved a search of electronic databases (Medline, EMBASE, PubMed, CINAHL) to identify and appraise studies of interest utilising the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. To further ameliorate the accuracy of our analysis we included an additional unpublished cohort of CH patients recruited at a tertiary referral centre for headache, who underwent detailed family history with diagnostic verification in relatives. Data was extracted and meta-analysis conducted to provide a true estimation of family history. Results: In total, we identified 7 studies which fulfilled our inclusion criteria. The estimated true prevalence of CH patients with a positive family history was 6.27% (95% CI:4.65-8.40%) with an overall I 2 of 73% . Fitted models for gender subgroups showed higher estimates 9.26% (95% CI: 6.29-13.43%) in females. However the I 2 for the female model was 58.42% and significant (p=0.047). Conclusion: Our findings estimate a rate of family history in CH to be approximately 6.27% (95% CI:4.65-8.40%) . While estimates were larger for female probands, we demonstrated high heterogeneity in this subgroup. These findings further support a genetic role in the aetiology of CH.

show abstract

“…A number of the early articles on headache disorders were published by Farias da Silva and coworkers in the scientific journal Neurobiologia (Recife), which is one of the oldest journals in the area of neurology in Latin America, founded in 1943 by Ulysses Pernambucano. Another important journal containing articles on headache written by Brazilians is Arquivos de Neuropsiquiatria , which was founded in 1945 …”

Section: Publications In Headache Medicinementioning

confidence: 99%

Headache Research and Medical Practice in Brazil: An Historical Overview

2015

View full text Add to dashboard Cite

Since the creation of the Brazilian Headache Society in 1978, substantial developments have taken place in both research and clinical practice in the field of headache medicine in Brazil. The Society now has almost 300 members throughout the country, actively working to improve the health of the general population and, in particular, diagnose and treat headache disorders. In addition, in a few large cities, such as São Paulo, Rio de Janeiro, Recife, Ribeirão Preto, Curitiba, and Porto Alegre, headache specialists have come together to promote research projects and increase knowledge in the field through MSc, PhD, and postdoctoral programs. Furthermore, scientific journals have emerged and books have been published to record and disseminate Brazilian scientific production in headache medicine. In this narrative review, we will briefly describe some important aspects of headache medicine in Brazil from prehistoric times to the present day, discuss the origin of headache medicine as a specialty in Brazil, the principal publications dealing with headache disorders, the use of plants and other unconventional forms of treatment used by faith healers, the main training centers, and the research produced to date by Brazilians. In conclusion, in recent years enormous progress has been made in headache medicine in Brazil stimulating us to review and expand our role in an increasingly international scenario.

show abstract

Familial aggregation of cluster headache

Cited by 11 publications

References 22 publications

Prevalence of familial cluster headache: a systematic review and meta-analysis

Prevalence of familial cluster headache: a systematic review and meta-analysis

Prevalence of Familial Cluster Headache: A Systematic Review and Meta-Analysis

Headache Research and Medical Practice in Brazil: An Historical Overview

Contact Info

Product

Resources

About