Falls: descriptive rates and circumstances in age-unspecified patients with locally advanced esophageal cancer

Childs, Daniel S; Yoon, Harry H.; Eiring, Rachel A.; Jin, Zhaohui; Jochum, Jacob A.; Pitot, Henry C.; Jatoi, Aminah

doi:10.1007/s00520-020-05511-z

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…The study showed that QLQ-CIPN20 mediates the role between CIPN grade and PAIS-SR. Our study shows that the quality of life of patients becomes worse due to the severity of CIPN, thus decreasing their level of psychosocial adjustment. Childs et al [ 29 ] showed that patients with esophageal cancer suffer from neurotoxic symptoms such as weakness in both lower limbs and dizziness at the chemotherapy stage. These symptoms lead to adverse events such as falls and disruption of daily activities, decreasing the quality of life of patients and creating psychosocial maladjustment.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial adaptation and influencing factors among patients with chemotherapy-induced peripheral neuropathy

Zhou¹,

Wang²,

Ding³

et al. 2022

WJCC

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BACKGROUND Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and long-lasting side effect caused by various anticancer agents that damage sensory, motor and autonomic nerves. It can cause maladaptive behaviors, including disease severity, anxiety, depression, sleep disorders, falls, and social impairment. These disorders have physical, psychological and social effects on patients and can seriously influence their quality of life. AIM To investigate the current situation of psychosocial adaptation to the disease and its influencing factor in patients with CIPN. METHODS A convenience sampling method was used to select 233 patients with CIPN in our hospital from February to August 2021. In addition, a cross-sectional survey was conducted using a sociodemographic questionnaire, the Self-Report Psychosocial Adjustment to Illness Scale, and the European Organisation for the Research and Treatment of Cancer Quality of Life CIPN20 (QLQ-CIPN20). Factors influencing psychosocial adaptation in patients with CIPN were analyzed by t -test or one-way analysis of variance, correlation analysis, multiple stepwise regression analysis, and structural equation models. RESULTS The psychosocial adaptation score of patients with CIPN was 52.51 ± 13.18. Multivariate analysis showed that autonomic nerves, tumor stage, motor nerves, education level, availability of caregivers, semi-retirement status, CIPN grade were independent risk factors for patients with CIPN ( P < 0.05). Structural equation models showed that QLQ-CIPN20 mediated the relationship between CIPN grade, tumor stage, and psychosocial adaptation. CONCLUSION Patients with CIPN have poor psychosocial adaptation and are affected by a variety of physiological, psychological, and social factors. Patients’ adaptive responses should be assessed, and targeted interventions implemented.

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Section: Discussionmentioning

confidence: 99%

Psychosocial adaptation and influencing factors among patients with chemotherapy-induced peripheral neuropathy

Zhou¹,

Wang²,

Ding³

et al. 2022

WJCC

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“…We considered patients 60-years-old with stage I to III ESCC who received a treatment intervention as the target population because the studies displayed that most patients with esophageal cancer develop the disease in the aged 50 to 70 years [ 12 , 26 , 27 ]. Also, the medical records at the cancer institute of Iran demonstrated that the average age of ESCC patients was about 60-years.…”

Section: Methodsmentioning

confidence: 99%

A cost-effectiveness modeling study of treatment interventions for stage I to III esophageal squamous cell carcinoma

Daroudi

Nahvijou

Arab

et al. 2022

Cost Eff Resour Alloc

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Background Esophageal cancer causes considerable costs for health systems. Appropriate treatment options for patients with esophageal squamous cell carcinoma (ESCC) can reduce medical costs and provide more improved outcomes for health systems and patients. This study evaluates the cost-effectiveness of treatment interventions for patients with ESCC according to the Iranian health system. Material and methods A five-state Markov model with a 15-year time horizon was performed to evaluate the cost-effectiveness of treatment interventions based on stage for ESCC patients. Costs ($US 2021) and outcomes were calculated from the Iranian health system, with a discount rate of 3%. One-way sensitivity analyses were performed to assess the potential effects of uncertain variables on the model results. Results In stage I, the Endoscopic Mucosal Resection (EMR) treatment yielded the lowest total costs and highest total QALY for a total of $1473 per QALY, making it the dominant strategy compared with esophagectomy and EMR followed by ablation. In stages II and III, chemoradiotherapy (CRT) followed by surgery dominated esophagectomy. CRT followed by surgery was also cost-effective with an incremental cost-effectiveness ratio (ICER) of $2172.8 per QALY compared to CRT. Conclusion From the Iranian health system’s perspective, EMR was the dominant strategy versus esophagectomy and EMR followed by ablation for ESCC patients in stage I. The CRT followed by surgery was a cost-effective intervention compared to CRT and esophagectomy in stages II and III.

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Falls: descriptive rates and circumstances in age-unspecified patients with locally advanced esophageal cancer

Cited by 2 publications

References 15 publications

Psychosocial adaptation and influencing factors among patients with chemotherapy-induced peripheral neuropathy

Psychosocial adaptation and influencing factors among patients with chemotherapy-induced peripheral neuropathy

A cost-effectiveness modeling study of treatment interventions for stage I to III esophageal squamous cell carcinoma

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