2009
DOI: 10.1186/1472-6963-9-228
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Fall-related injuries in a nursing home setting: is polypharmacy a risk factor?

Abstract: BackgroundPolypharmacy is regarded as an important risk factor for fallingand several studies and meta-analyses have shown an increased fall risk in users of diuretics, type 1a antiarrhythmics, digoxin and psychotropic agents. In particular, recent evidence has shown that fall risk is associated with the use of polypharmacy regimens that include at least one established fall risk-increasing drug, rather than with polypharmacy per se. We studied the role of polypharmacy and the role of well-known fall risk-incr… Show more

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Cited by 93 publications
(72 citation statements)
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“…The goal of the protocol is expeditious but safe care of these patients with hip fractures and multiple comorbidities. [16][17][18] A standardized order set was developed and is utilized in the emergency department as well as for admission to the hospital, postoperatively, and for discharge. Particular attention was paid to avoidance of contraindicated medications [19][20][21] that have been demonstrated to increase the risk of delirium in the elderly patient and often increase hospital length of stay.…”
Section: Methodsmentioning
confidence: 99%
“…The goal of the protocol is expeditious but safe care of these patients with hip fractures and multiple comorbidities. [16][17][18] A standardized order set was developed and is utilized in the emergency department as well as for admission to the hospital, postoperatively, and for discharge. Particular attention was paid to avoidance of contraindicated medications [19][20][21] that have been demonstrated to increase the risk of delirium in the elderly patient and often increase hospital length of stay.…”
Section: Methodsmentioning
confidence: 99%
“…Conditions associated with fractures include (1) age over 85 yr; (2) agitated behavior; (3) use of a wheelchair, cane, or walker; (4) medications, including anticonvulsants, antidepressants, opioids, iron supplements, bisphosphonates, thiazides, and laxatives; and (5) polypharmacy [14][15]. Polypharmacy has been implicated in injurious falls in older adults who reside in a community, although randomized controlled trials are lacking to provide conclusive evidence [16].…”
Section: Introductionmentioning
confidence: 99%
“…Often, geriatric patients with lower extremity fractures have preexisting comorbidities that may have predisposed them to the fall that caused the fracture: dehydration, chronic urinary tract infection, dementia, and disequilibrium due to polypharmacy or other factors. 10,11 These comorbidities need optimization prior to and after surgical repair of the fractures, and may increase the risk of morbidity and mortality associated with the surgical repair.…”
Section: Introductionmentioning
confidence: 99%