Fall of another myth for colon cancer: Duration of symptoms does not differ between right- or left-sided colon cancers

Öztürk, Ersin; Kuzu, Mehmet Ayhan; Öztuna, Derya; Işık, Özgen; Canda, Aras Emre; Balık, Emre; Erkasap, Serdar; Yoldaş, Tayfun; Akyol, Cihangir; Demirbaş, Sezai; Özoğul, Bünyamin; Topçu, Ömer; Gedik, Ercan; Baca, Bilgi; Ergüner, İlknur; Asoğlu, Oktar; Erkek, B.; Yılmazlar, Tuncay; Reis, Erhan; Gençosmanoğlu, Rasim; Konan, Ali

doi:10.5152/tjg.2019.17770

Cited by 4 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The difference in clinical presentations may have been one of the causes that could impact this behaviour of the primary care physician. Recent studies confirm that left-sided tumours have a more symptomatic presentation (haematochezia, rectal symptoms) and this may mean it is not as necessary to request further tests that target the origin of the colon symptoms [17]. However, the most common right CRC symptoms are latent or nonspecific (such as abdominal pain, ferropoenic anaemia or altered bowel habit) which most commonly have nontumour aetiology.…”

Section: Implications For Physicians and Managersmentioning

confidence: 99%

Faecal Immunochemical Test Impact on Prognosis of Colorectal Cancer Detected in Symptomatic Patients

et al. 2022

View full text Add to dashboard Cite

The use of the faecal immunochemical test (FIT) to stratify the risk of colorectal cancer (CRC) in symptomatic patients in primary healthcare enables improved referrals to colonoscopy. However, its effect on diagnostic delays or the prognosis of patients has been poorly evaluated in this setting. We performed a retrospective cohort study that included symptomatic patients with outpatient CRC diagnosis between 2009 and 2017. We identified whether FIT had been analysed between initial healthcare contact and diagnostic confirmation. We included 589 patients (male = 65%, 71.7 ± 11.6 years, TNM IV = 17.1%) in the analysis. FIT was performed in 411 (69.8%) patients with a positive result (≥10 µg/g of faeces) in 96.4% of the evaluated patients. The use of FIT was associated with increased diagnostic delay (yes = 159 ± 277 days, no = 111 ± 172 days; p = 0.01). At five years follow up, 193 (32.8%) patients died (151 due to CRC). Mean survival was not modified by the use of FIT or its result (not performed = 46.8 ± 1.5 months, FIT+ = 48.9 ± 1 months, FIT− = 45.6 ± 5.5 months; p = 0.5) in Kaplan–Meier analysis, and was confirmed later in multivariate Cox regression analysis. In conclusion, FIT determination in symptomatic patients in primary healthcare did not modify CRC prognosis.

show abstract

Section: Implications For Physicians and Managersmentioning

confidence: 99%

Faecal Immunochemical Test Impact on Prognosis of Colorectal Cancer Detected in Symptomatic Patients

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Certain clinicopathological factors are associated with anaemia in CRC patients. These include age, American Society of Anesthesiologists (ASA) classification, tumour stage, tumour site, nutritional status and ongoing inflammation [5,10,[14][15][16][17][18]. Few studies have examined their association with iron deficiency [5,7,10,11].…”

mentioning

confidence: 99%

Iron deficiency in colorectal cancer patients: a cohort study on prevalence and associations

et al. 2020

View full text Add to dashboard Cite

Anaemia and iron deficiency are common manifestations of colorectal cancer (CRC). The reported prevalence of anaemia at diagnosis of CRC is between 23% and 56%, with 70-80% due to iron deficiency [1][2][3][4][5][6][7]. Studies have shown that anaemia is associated with an increased risk of postoperative complications, mortality and cancer recurrence [8][9][10][11] following CRC surgery. Low iron stores have even been shown to be a significant risk factor for postoperative infections and increased length of hospital stay following gastrointestinal surgery [12]. Iron deficiency may adversely affect overall survival, relapse-free survival and postoperative complication rates after

show abstract

A systematic review of methodological considerations in time to diagnosis and treatment in colorectal cancer research

Drosdowsky

Lamb

Bergin

et al. 2023

Cancer Epidemiology

View full text Add to dashboard Cite

Fall of another myth for colon cancer: Duration of symptoms does not differ between right- or left-sided colon cancers

Cited by 4 publications

References 22 publications

Faecal Immunochemical Test Impact on Prognosis of Colorectal Cancer Detected in Symptomatic Patients

Faecal Immunochemical Test Impact on Prognosis of Colorectal Cancer Detected in Symptomatic Patients

Iron deficiency in colorectal cancer patients: a cohort study on prevalence and associations

A systematic review of methodological considerations in time to diagnosis and treatment in colorectal cancer research

Contact Info

Product

Resources

About