Failure of the Circulation

Circulatory Dynamics Before and After Exercise in Subjects With and Without Structural Heart Disease During Anxiety and Relaxation 1

“…Further, the excess work in the patients with anxiety was associated with considerable tachycardia. Harrison has reviewed the ample evidence of the penalties paid by the heart which is operating at excessive rates (18). The tachycardia of the patients with anxiety here was perhaps not great, their heart rates averaging only 102 at two minutes after the exercise.…”

Experimental Hypervolemic Heart Failure: Its Bearing on Certain General Principles of Heart Failure

“…T HE PURPOSES of the present communication are threefold: (1) to present experimental data concerning a type of heart failure to which relatively little attention has been paid in the past; (2) to consider the similarities between heart failure produced experimentally and that occurring in patients; (3) to offer a classification of heart failure which appears to be applicable to both con-ditions.…”

“…In the heart-lung preparation, failure may be induced by (1) gradual exhaustion of the myocardium, (2) excessive increase in the peripheral resistance, (3) excessive elevation of the venous reservoir. The first factor is the most important because it occurs spontaneously with the passage of time, and because the myocardial competence determines at all times the degree of load (arterial or venous) which is required to produce failure.…”

The Lewis A. Conner Memorial Lecture

“…23 Relatively retarded blood flow, increasing anoxia and acidity in the respiratory center would induce hyperpnea; and the prolongation of the hyperpneic state during the recovery period, so characteristic a feature of cardiac dyspnea, was explained by the slow restoration of tissues to their metabolic resting state.…”