Failure Mechanisms in Total Hip and Knee Arthroplasty: A Morphologic and Radiologic Study

Barden, B.; Huttegger, C.

doi:10.1002/(sici)1521-4052(199912)30:12<746::aid-mawe746>3.0.co;2-3

Cited by 7 publications

(2 citation statements)

References 16 publications

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“…The phenomenon of asymptomatic or painless implant loosening is well known. In a failure analysis of 451 total hip arthroplasties (Barden and Huttegger, 1999) about 16.4% sustain an asymptomatic loosening.…”

Section: Resultsmentioning

confidence: 99%

Localization of SP‐ and CGRP‐immunopositive nerve fibers in the hip joint of patients with painful osteoarthritis and of patients with painless failed total hip arthroplasties

Saxler

Löer

Skumavc

et al. 2007

European Journal of Pain

104

112

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Using immunohistochemical methods we determined the presence of SP- and CGRP-immunopositive nerve fibers in the hip joint of patients with femoral neck fracture (controls, group 1), painful osteoarthritis (group 2), and painless failed total hip arthroplasties (group 3). Immunoreactive nerve fibers were found in the soft tissue of the fossa acetabuli as well as in the subintimal part of the synovial layer in the hip joint capsule of groups 1 and 2. In the capsule of controls the innervation density had a median of 5.7fibers/cm(2) for CGRP-ir and 3.2fibers/cm(2) for SP-ir afferents. In the osteoarthritic group, the density significantly increased to a median of 15.6fibers/cm(2) for CGRP-ir and 8.2fibers/cm(2) for SP-ir neurons (p=0.05). Patients with failed hip arthroplasties completely lacked these neuropeptide containing afferents. Innervation density in the fossa acetabuli of osteoarthritc patients showed a median of 14.1fibers/cm(2) for CGRP-ir and 5.9fibers/cm(2) for SP-ir afferents. From these data we assume that the hip joint capsule and the soft tissue of the fossa acetabuli are important triggers of nociception. This is supported by the fact, that patients with loosened total hip arthroplasties, where we failed to detect SP- and CGRP-immunoreactive fibers, did not feel pain. The upregulation of SP- and CGRP-positive neurons in response to arthritic stages suggests a mechanism involving neuropeptides in the maintenance of a painful degenerative joint disease and in mediating noxious stimuli from the periphery. Furthermore, these findings help to explain clinical observations, such as effectiveness of local therapy to control hip pain with intraarticular injection, synovectomy and denervation procedures.

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Section: Resultsmentioning

confidence: 99%

Localization of SP‐ and CGRP‐immunopositive nerve fibers in the hip joint of patients with painful osteoarthritis and of patients with painless failed total hip arthroplasties

Saxler

Löer

Skumavc

et al. 2007

European Journal of Pain

104

112

View full text Add to dashboard Cite

show abstract

“…T oday, more than 600,000 total hip and knee arthroplasties are being performed annually in Europe and the United States Barden, (1998). It has been found that in India alone, about 7 crore people suffer from joint related problems and this incidence is expected to rise Wadhwa, (2008).…”

Section: Introductionmentioning

confidence: 99%

Preparation and Deposition of Hydroxyapatite on Biomaterials by Sol-Gel Technique-A Review

Kaur¹,

Bala²,

Khosla³

2013

CCR

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Hydroxyapatite Ca 10 (PO 4) 6 (OH) 2 (HAP) is an important inorganic biomaterial which has attracted the attention of researchers in recent years. Due to its chemical and structural similarity with the mineral phase of bone and teeth, it is widely used for hard tissues repair. Amongst various methods, sol-gel technique has achieved more popularity recently due to synthesis of ceramics powders. The sol-gel process is easily applicable to surface coating as it allows the preparation of high-quality HA thin films on metal substrates. It has been observed from the studies that the protective atmosphere during sintering process accomplished after sol-gel coating produces good uniformity of coating material which significantly leads to a reduction in the porosity of the coating film. In another study it was revealed that mechanical properties of commercial HAP can be significantly improved by adding P 2 O 5 and Na 2 CO 3 without altering its biocompatibility. It has been found from the extensive literature review that homogeneous and crack-free coatings were obtained on biocompatible substrate implant at higher sintering temperatures. The particle size of the HAP powder increases with the increase of the sintering time and sintering temperature. In this paper a review of the studies done for the preparation and deposition of HAP powder with the solgel technique has been detailed.

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Adhesion enhancement of steel fibers to acrylic bone cement through a silane coupling agent

Kotha

Lieberman

Vickers

et al. 2005

J Biomedical Materials Res

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The use of a silane coupling agent (methacryloxypropyl-trichlorosilane) to improve the mechanical properties of steel fiber-reinforced acrylic bone cements was assessed. Changes to the tensile and fracture properties of bone cements reinforced with silane-coated or uncoated 316L stainless steel fibers of different aspect ratios were studied. Contact-angle measurements indicated that the coupling agent coats the metal surface through room temperature treatments in a short time (within 2 h). Push-out tests indicated that the interfacial shear strength of silane-coated 316L stainless steel rods is 141% higher than the uncoated rods. The elastic moduli, ultimate stresses, and fracture toughness of the silane-coated, steel fiber-reinforced bone cements are significantly higher than the bone cements reinforced with uncoated steel fibers. There were no differences in the tensile mechanical properties of the silane-coated or uncoated, steel fiber-reinforced cements after aging in a physiological saline solution, indicating that the bonding effectiveness is decreased by the intrusion of water at the metal-polymer interface. Because of possible biocompatibility issues with leaching of the silane coupling agent and no long-term mechanical benefit in simulated aging experiments, the use of these agents is not recommended for in vivo use.

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Failure Mechanisms in Total Hip and Knee Arthroplasty: A Morphologic and Radiologic Study

Cited by 7 publications

References 16 publications

Localization of SP‐ and CGRP‐immunopositive nerve fibers in the hip joint of patients with painful osteoarthritis and of patients with painless failed total hip arthroplasties

Localization of SP‐ and CGRP‐immunopositive nerve fibers in the hip joint of patients with painful osteoarthritis and of patients with painless failed total hip arthroplasties

Preparation and Deposition of Hydroxyapatite on Biomaterials by Sol-Gel Technique-A Review

Adhesion enhancement of steel fibers to acrylic bone cement through a silane coupling agent

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