The present study conducts experimental, numerical and analytical investigations on the responses of double-layer Steel-RULCC-Steel sandwich panels subjected to concentrated impact loading. Seven full-scale SCS panels are designed and fabricated with different number of concrete layers, degree of composite action, type of shear connectors, and proportion of added rubber powder. The influences of these design parameters on the failure mode and response behavior are quantified and discussed. Advanced FE simulation is performed in LS-DYNA to extract more information on the strains, stresses, and energy absorption of the panel during the impact. Finally, a single-degree-of-freedom (SDOF) model and a two-degree-of-freedom (TDOF) model are developed to predict displacement-time and load-time responses of the double-layer SCS panels based on the quasi-static load-displacement relationship proposed also in this paper. The comparisons with test results demonstrate that the SDOF model overpredicts the peak deformation of the panel if the hammer weight is much larger than the effective panel weight. In contrast, both the FE model and TDOF model provide a much more accurate prediction on the impact responses of double-layer SCS panels, including the peak impact force, peak deformation, and residual deformation.