Failure analysis of a modular revision total HIP arthroplasty femoral stem fractured in vivo

Ortega, Pina; Medeiros, W. B.; Moré, Ari Digiácomo Ocampo; Vasconcelos, R.F.; Rosa, Edison da; Roesler, Carlos Rodrigo de Mello

doi:10.1016/j.engfailanal.2020.104591

Cited by 8 publications

(3 citation statements)

References 28 publications

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“…Previous attempts to predict fatigue failure in medical implants using numerical models can be found in literature. In a recent study (Ortega et al, 2020), a finite element analysis (FEA) was performed that showed a stress concentration consistent with the experimentally observed location of crack initiation. In addition, the fatigue life of a hip implant and orthopedic plates were also recently investigated by comparing experiments and a linear elastic FEA in (Babić et al, 2020), (Parr et al, 2021).…”

Section: Introductionmentioning

confidence: 56%

Experimental analysis and numerical fatigue life prediction of 3D-Printed osteosynthesis plates

Nakhaei¹,

Sterba²,

Foletti

et al. 2023

Front. Bioeng. Biotechnol.

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The trend towards patient-specific medical orthopedic prostheses has led to an increased use of 3D-printed surgical implants made of Ti6Al4V. However, uncertainties arise due to varying printing parameters, particularly with regards to the fatigue limit. This necessitates time-consuming and costly experimental validation before they can be safely used on patients. To address this issue, this study aimed to employ a stress-life fatigue analysis approach coupled with a finite element (FE) simulation to estimate numerically the fatigue limit and location of failure for 3D-printed surgical osteosynthesis plates and to validate the results experimentally. However, predicting the fatigue life of 3D components is not a new concept and has previously been implemented in the medical device field, though without experimental validation. Then, an experimental fatigue test was conducted using a proposed modification to the staircase method introduced in ISO 12107. Additionally, a FE model was developed to estimate the stress cycles on the plate. The stress versus number of cycles to failure curve (S-N) obtained from the minimum mechanical properties of 3D-printed Ti6AI4V alloy according to ASTM F3001-14 to predict the fatigue limit. The comparison between experimental results and fatigue numerical predictions showed very good agreement. It was found that a linear elastic FE model was sufficient to estimate the fatigue limit, while an elastic-plastic model led to an accurate prediction throughout the implant’s cyclic life. The proposed method has great potential for enhancing patient-specific implant designs without the need for time-consuming and costly experimental regulatory testing.

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Section: Introductionmentioning

confidence: 56%

Experimental analysis and numerical fatigue life prediction of 3D-Printed osteosynthesis plates

Nakhaei¹,

Sterba²,

Foletti

et al. 2023

Front. Bioeng. Biotechnol.

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“…Titanium (Ti) and Ti-alloys such as Ti6Al4V are broadly considered for orthopedic and dental implant application . However, fatigue fracture of Ti implants under cyclic loads possibly leads to implant failure and secondary damage to the patients. , In addition, vanadium (V) and aluminum (Al) elements released from Ti6Al4V implants would induce long-term health illnesses such as peripheral neuropathy, osteomalacia, and Alzheimer’s disease. , Bacterial infection also results in implant failure. In the full joint substitute of the knee, hip, and ankle, the infectivity rates of periprosthetic joint disease were up to 0.5–2, 2–9, and 0.3–1.7% respectively.…”

Section: Introductionmentioning

confidence: 99%

“…1 However, fatigue fracture of Ti implants under cyclic loads possibly leads to implant failure and secondary damage to the patients. 2,3 In addition, vanadium (V) and aluminum (Al) elements released from Ti6Al4V implants would induce longterm health illnesses such as peripheral neuropathy, osteomalacia, and Alzheimer's disease. 4,5 Bacterial infection also results in implant failure.…”

Section: Introductionmentioning

confidence: 99%

Corrosion Behavior and Bio-Functions of the Ultrafine-Grained Ti6Al4V-5Cu Alloy with a Dual-Phase Honeycomb Shell Structure in Simulated Body Fluid

Liu

Siddiqui

et al. 2023

ACS Biomater. Sci. Eng.

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Titanium alloys are widely used in biomedical applications. However, cases of implant failure due to fatigue fracture and bacterial infection are common. In addition, implants are susceptible to metal ions (Al, V) released by long-term exposure to human body fluids, which causes neuropathy, mental disorders, and other diseases. Thus, development of novel materials to achieve longterm safety of implants is currently a research hotspot. Recently, our research group has developed an ultrafine-grained Ti6Al4V-5Cu alloy with a unique "dual-phase honeycomb shell" (DPHS) structure, which possesses high fatigue strength and stability. This study further affirmed its higher corrosion behavior, antibacterial properties, and cytocompatibility compared to the coarse-grained Ti6Al4V and Ti6Al4V-5Cu alloys. The ultrafine-grained structure of Ti6Al4V-5Cu having DPHS increased the proportion of phases (Cu-rich phases, β-phase, and Ti 2 Cu intermetallic phase) with a lower surface potential. It was observed that the developed microstructure was conducive to a stable configuration of the oxide (passive) layer on the alloy surface. In addition, the low-phase interfacial energies of the ultrafine-grained structure with DPHS even facilitated the improvement of the denseness of the protective passive film and eventually enhanced the corrosion behavior. Besides, the fine-Cu-rich phases and the micro-galvanic couples formed between them and the matrix significantly increased the contact frequency of bacteria, thus increasing the contact sterilization efficiency of the ultrafine-grained Ti6Al4V-5Cu alloy. These results showed that the new ultrafine-grained Ti6Al4V-5Cu alloy has excellent corrosion resistance and biological functions for clinical application.

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Failure analysis of an in-vivo fractured patient-specific Ti6Al4V mandible reconstruction plate fabricated by selective laser melting

Shi

Sun

Yang

et al. 2021

Engineering Failure Analysis

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Failure analysis of a modular revision total HIP arthroplasty femoral stem fractured in vivo

Cited by 8 publications

References 28 publications

Experimental analysis and numerical fatigue life prediction of 3D-Printed osteosynthesis plates

Experimental analysis and numerical fatigue life prediction of 3D-Printed osteosynthesis plates

Corrosion Behavior and Bio-Functions of the Ultrafine-Grained Ti6Al4V-5Cu Alloy with a Dual-Phase Honeycomb Shell Structure in Simulated Body Fluid

Failure analysis of an in-vivo fractured patient-specific Ti6Al4V mandible reconstruction plate fabricated by selective laser melting

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