Facts and myths pertaining to fibromyalgia

Haüser, Winfried; Fitzcharles, Mary Ann

doi:10.31887/dcns.2018.20.1/whauser

Cited by 150 publications

(89 citation statements)

References 62 publications

(60 reference statements)

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“…The average global prevalence of FM is 2.4%, with notable variations by country; from 0.4% in Greece to 9.3% in Tunisia [ 3 ]. FM can affect any age and the female-to-male ratio is 8–10:1 [ 4 ], although most are women between 40 and 60 years old [ 5 ]. In addition, fibromyalgia syndrome is associated with a significant burden on the individual and society [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Suicidal Ideation Profiles in Patients with Fibromyalgia Using Transdiagnostic Psychological and Fibromyalgia-Associated Variables

Ordóñez-Carrasco

Sánchez-Castelló

Calandre

et al. 2020

IJERPH

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Several studies have emphasized the heterogeneity of fibromyalgia patients. Furthermore, fibromyalgia patients are considered a high-risk suicide group. The ideation-to-action framework proposes a set of transdiagnostic psychological factors involved in the development of suicidal ideation. The present study aims to explore the existence of different subgroups according to their vulnerability to suicidal ideation through these transdiagnostic psychological variables and a set of variables typically associated with fibromyalgia. In this cross-sectional study, 151 fibromyalgia patients were assessed through the Revised Fibromyalgia Impact Questionnaire, Beck Depression Inventory-II, Plutchik Suicide Risk Scale, Interpersonal Needs Questionnaire, Defeat Scale, Entrapment Scale, Psychache Scale, and Beck Hopelessness Scale. A K-means cluster analysis identified two clusters, one (45.70%) according to a low vulnerability, and a second (54.30%) with a high vulnerability to suicidal ideation. These clusters showed statistically significant differences in suicidal ideation and suicide risk. However, no differences were observed in most socio-demographic variables. In conclusion, fibromyalgia patients who present a clinical condition characterized by a moderate-high degree of physical dysfunction, overall disease impact and intensity of fibromyalgia-associated symptoms, along with a high degree of perceived burdensomeness, thwarted belongingness, defeat, entrapment, psychological pain and hopelessness, form a homogeneous group at high risk for suicidal ideation.

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Section: Introductionmentioning

confidence: 99%

Suicidal Ideation Profiles in Patients with Fibromyalgia Using Transdiagnostic Psychological and Fibromyalgia-Associated Variables

Ordóñez-Carrasco

Sánchez-Castelló

Calandre

et al. 2020

IJERPH

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“…It is well known the frequent functional and psychiatry comorbidities in fibromyalgia that can negatively affect the patients' mood [ 16 , 17 ]. Additionally, they are a particular population with low access to healthcare and constant debilitating pain and fatigue decreasing their quality of life [ 59 , 60 ]. Therefore, the emotional support in these patients could increase the resilience and adaptation to the disease and facilitate the seek for novel therapies.…”

Section: Discussionmentioning

confidence: 99%

Barriers and facilitators for clinical trial participation of underrepresented and non-underrepresented fibromyalgia patients: A cross-sectional internet survey

Cardenas-Rojas

Pacheco‐Barrios

Castelo-Branco

et al. 2021

Heliyon

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Background: There is a need of well-powered randomized clinical trials in fibromyalgia. However, challenges for recruitment are presented. This study aims to describe and assess the perception of barriers and facilitators and the associated factors for the participation of underrepresented and non-underrepresented fibromyalgia patients. Methods: We performed an online survey through REDCap (Research Electronic Data Capture) targeting fibromyalgia patients from April 7 to July 3, 2020 during the COVID-19 stay home mandate and it was restricted to the United States of America. We described and compared the survey characteristics between underrepresented and non-underrepresented participants, and we performed logistic regression models to assess the associated factors with clinical trial participation. Results: In total, 481 completed the survey including 168 underrepresented fibromyalgia patients. Only (1) 11.09 % reported previous participation in clinical trials and the significant perceived barriers were investigator-related (lack of friendliness of research staff and the opportunity to receive the results) and center-related (privacy and confidentiality policies, and the institution's reputation); (2) the participation rate and perceived barriers and facilitators were similar between underrepresented and non-underrepresented patients; and was positively associated with low income, higher age, and clinical trial awareness from their physician; and negatively associated with the perception of investigator-related barriers; and (4) for the underrepresented population, the presence of emotional support. Conclusion: Our findings suggest low rates of participation, regardless of underrepresented population status. Strategies as involving their physician as liaison to increase the awareness of clinical trials, as well as improving patient-researcher communication should be considered in this population.

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“…These patients were excluded from the study as it could not be concluded whether they had psychogenic or non-psychogenic conditions as of March 2020. [ 10 11 12 13 ] Besides, three middle-aged female patients who were eventually diagnosed with the postmenopausal syndrome were also excluded from this study because of the difficulty of objectively diagnosing the disorder solely based on laboratory and physiological diagnostic examinations. [ 14 ] Consequently, the remaining 277 patients with persistent physical symptoms were considered eligible for the study.…”

Section: Methodsmentioning

confidence: 99%

Somatic symptoms with psychogenic or psychiatric background

Akaishi

Abe

Masaura

et al. 2021

Journal of Family Medicine and Primary Care

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Introduction: The characteristics of somatic symptoms seen at the first hospital visit in patients with psychogenic backgrounds remain poorly elucidated till date. Methodology: A total of 277 patients who visited the Department of General Medicine at a single university hospital with somatic symptoms were prospectively enrolled in this study. The eventual definite diagnoses were classified into the following three groups: non-psychogenic disease ( n = 128), psychogenic symptoms ( n = 131), and mental illness ( n = 18). Subsequently, the chief complaints and other background information of the patient obtained at the first visit were compared among the three groups. Results: More than half of the patient with non-psychogenic diseases (60.2%) presented with a single complaint at their first hospital visit; contrarily, less than half of the patients with psychogenic symptoms (23.7%) or mental illnesses (22.2%) presented with a single complaint at the first visit. Approximately, <10% of the patients with non-psychogenic diseases had four or more multisystemic presentations at the first visit. The results of the receiver operating characteristic curve analysis revealed a fair discriminatory ability of the number of complaints to identify patients with psychogenic diseases or psychiatric backgrounds. Almost half of the non-psychogenic patients with four or more multisystemic presentations were eventually diagnosed with autoimmune-related disorders, such as Sjögren's syndrome or Behçet's disease. In conclusion, the general notion that patients with psychogenic somatic symptoms are likely to present with more complaints than patients with non-psychogenic diseases is correct. However, not a few patients who present with multiple indefinite complaints would certainly have organic diseases such as autoimmune-related disorders or neuromuscular diseases. A careful diagnostic process is required in such patients before attributing their symptoms to psychogenic or psychiatric factors.

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Facts and myths pertaining to fibromyalgia

Cited by 150 publications

References 62 publications

Suicidal Ideation Profiles in Patients with Fibromyalgia Using Transdiagnostic Psychological and Fibromyalgia-Associated Variables

Suicidal Ideation Profiles in Patients with Fibromyalgia Using Transdiagnostic Psychological and Fibromyalgia-Associated Variables

Barriers and facilitators for clinical trial participation of underrepresented and non-underrepresented fibromyalgia patients: A cross-sectional internet survey

Somatic symptoms with psychogenic or psychiatric background

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