Facts about Fats: New Insights into the Role of Lipids in Metabolism, Disease and Therapy

Abstract

Although initially regarded as a passive system to store energy, lipids are now considered to play crucial, structural and functional roles in almost all the biological processes involved in the regulation of physiological and pathological conditions [...]

Develop a stepwise integrated method to screen biomarkers of Baihe‐Dihuang Tang on the treatment of depression in rats applying with composition screened, untargeted, and targeted metabolomics analysis

“…This was consistent with the findings of previous studies where the nervous system of CUMS rats was disturbed to a certain extent [22][23][24]. Although initially regarded as a passive system to store energy, lipids are now considered to play crucial, structural, and functional roles in almost all the biological processes involved in the regulation of physiological and pathological conditions [25]. Lipid metabolism is involved in many biological processes and plays a vital role in nervous system control, and lipid disorder is a common phenomenon in depression [21].…”

“…The phenylalanine transaminases that activate the phenylalanine metabolic bypass produce phenylketonate, making tyrosine levels significantly lower, and the ability to produce euphoria is reduced. The change of NE is related to the monoamine hypothesis of depression, which was first pro-posed 30 years ago, and proposed that the underlying biological basis of depression is the lack of central noradrenergic and/or serotonergic systems [25]. BDT may play an antidepressant role by modulating levels of these metabolites (Supporting information Figure S8).…”

Butanol Extract of Acanthopanax senticosus (Rupr. et Maxim.) Harms Alleviates Atherosclerosis in Apolipoprotein E‐Deficient Mice Fed a High‐Fat Diet

“…[22 -23] As one of the important macromolecular substances in organisms, lipids regulate various living processes, including energy conversion, transmission, apoptosis, material transport, and information recognition. [24] The pathological process of atherosclerosis is closely related to the deposition of lipids in the arterial wall by lipoproteins transporting lipids through the blood. Dyslipidemia is a major risk factor for atherosclerotic cardiovascular disease.…”

Actual aspects of sports nutrition in children

“…Кроме высокой энергетической ценности жиры, наравне с белками, выполняют роль пластического материала, так как входят в состав всех клеток и тканей организма. Кроме того, липиды способствуют лучшему использованию организмом белков, витаминов и минеральных веществ [7]. Питание…”