Abstract:<p>Rationale: +/- 3, 4-Methylenedioxymethamphetamine (MDMA; Ecstasy) consumption has increased globally over the past two decades. Human studies have demonstrated that in a small proportion of users MDMA consumption may become problematic. Limited preclinical studies have evaluated the abuse potential of MDMA. Objectives: The present study sought to determine if MDMA selfadministration has similar addictive properties as other abused substances. Initial experiments sought to determine if MDMA could funct… Show more
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