Factors Stimulating Function of Lymphaticovenous Communications

Lymphovenous shunts in man

“…The general view, as voiced for example by Le Gros Clark (1958) when reviewing the subject, has been that they exist at peripheral level in certain animals such as dogs, cats, squirrels, and South American monkeys, but not in man. More recently Pentecost et al (1966) have studied them in the dog, and Threefoot et al (1963) in the human cadaver.…”

Quantity of Lymph Nodes in the Vascularized Lymph Node Transfer Influences Its Lymphaticovenous Drainage

“…[27][28][29][30] Factors that stimulate the opening of these normally non-functioning peripheral lymphaticovenous connections include obstruction of major lymph channels, and increased intralymphatic volume or pressure. [28][29][30][31][32][33] In addition, several experimental and clinical studies evaluated the mechanism of peripheral lymphaticovenous shunting in the context of acute disruption of the lymphatic vessels. 29,30,34 Heymans et al studied flaps that do not contain lymph nodes in 14 patients.…”

Function of Liver and Other Organs During Lymphatic Obstruction in Sheep

“…If major lymph trunks are obstructed, lymph enters the bloodstream through these lymphatic-venous anastomoses, and clinical signs referable to lymphatic obstruction generally do not occur [Blalock et al, 1937;Threefoot, Pearson, Cabrera-Gil and Bradburn, 1967]. However, some authors have been able to impede the entry of lymph into the bloodstream, and have suggested that this may cause important alterations in structure and function [Blalock et al, 1937;Yoffey and Courtice, 1956;Csillik and F6ldi, 1967;Threefoot, Pearson, Cabrera-Gil and Bradburn, 1967]. This may be of particular importance during a period of local lymphatic obstruction in a transplanted organ [Malek, 1967].…”

“…5). An increase in the total concentration of white cells has been observed in dogs during the first few days after lymphatic obstruction, but the concentration oflymphocytes did decrease during this period [Threefoot, Pearson, Cabrera-Gil and Bradburn, 1967]. A number of authors have reported decreases in the lymphocyte concentration after lymphatic,obstruction [Yoffey and Courtice, 1956], but little information is available concerning the effect of other parts of the experimental procedure on the lymphocytes themselves or on the volume of plasma in which they are suspended.…”