Factors Related to Early Versus Late Hospital Arrival in Acute Ischemic Stroke

Abstract

Background: The onset-to-arrival time affects the decision of intravenous thrombolysis therapy which is associated with stroke’s prognosis. This study aimed to evaluate factor associated with early and late arrival of patients with Acute Ischemic Stroke and the effect on patients’ outcomes. Materials and Methods: Patients confirmed with acute ischemic stroke in central stroke centers were included in a prospective study. The patients were grouped into early arrivers (less than 4.5 hours) and late arrivers (at and after 4.5 hours). Patients’ data were obtained from the stroke registry system. Results: In Summary, Higher initial NIHSS, less than 15 km from the hospital, a history of CVA, Diabetes, Abnormal blood pressure, EMS transportation, Atrial fibrillation, and current use of anticoagulants, Not using opium, and not smoking was significantly associated with early arrival time. Normal blood pressure AF was a negative and significant (p-value=0.001, Odds ratio: 0.38) predictor of the late arrival. Normal blood pressure was a positive and significant (p-value<0.001, Odds ratio: 4.762) predictor of the late arrival. Conclusion: Some baseline factors are associated with the onset-arrival time of patients with ischemic stroke.