Factors related to depressive symptoms in older adult patients with type 2 Diabetes Mellitus

Filho, Bartolomeu Fagundes de Lima; Dias, Vanessa da Nóbrega; Carlos, Adriana Guedes; Fontes, Fabieli Pereira; Sousa, Anésio Mendes de; Gazzola, Juliana Maria

doi:10.1016/j.exger.2018.11.006

Cited by 5 publications

(9 citation statements)

References 27 publications

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“…The results showed that education level was significantly correlated with QoL in patients with diabetes. A higher education level could be linked with a better understanding of the disease and its impacts as well as better socioeconomic conditions, and better-educated patients were more likely to frequently seek appropriate medical advice and adhere to treatment programs and self-management [4,5,13]. People with paid employment and better financial security were more satisfied with their lives, which could lead to a better perception of QoL [22].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, it is necessary to assess the risk of disability among patients. Clinical strategies to alleviate disabilities (short-term moderately intense physical resistance exercise, blood glucose control, and nutrition education programs) could prevent and manage diabetes, meet the changing needs of patients with diabetes, and promote a support network to improve QoL [4,13].…”

Section: Discussionmentioning

confidence: 99%

“…Increased risk of disability is correlated with poor metabolic control and increased incidence of complications, which affect the QoL of the diabetic patients physiologically, psychologically, socially, and environmentally [11,12]. Therefore, early assessment of the risk of disability is crucial [13].…”

Section: Introductionmentioning

confidence: 99%

“…The five common domains of disability that affect the QoL of patients are movement, nutrition, cognition, sociability, and depression [4]. Related research has also found that fewer chronic diseases in patients with diabetes was linked with improved overall QoL [4,13], but patients with diabetes had double the likelihood of comorbidities compared with individuals without diabetes [4]. The Charlson comorbidity index (CCI) can predict 1 years' mortality rates and disease treatment outcomes, which can in turn determine quality-adjusted life years [16].…”

Section: Introductionmentioning

confidence: 99%

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Continuity of Care and the Quality of Life among Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Taiwan

Hsieh

Yang

et al. 2020

Healthcare

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Background: Understanding factors associated with the quality of life (QoL) of patients with type 2 diabetes (T2DM) is an important health issue. This study aimed to explore the correlation between continuity of care and quality of life in patients with T2DM and to probe for important explanatory factors affecting quality of life. Methods: This study used a cross-sectional correlation research design. Convenience sampling was adopted to recruit 157 patients, aged 20–80 years and diagnosed with T2DM in the medical ward of a regional hospital in central Taiwan. Results: The overall mean (standard deviation, SD) QOL score was 53.42 (9.48). Hierarchical regression linear analysis showed that age, depression, two variables of potential disability (movement and depression), and the inability to see a specific physician or maintain relational continuity with medical providers were important predictors that could effectively explain 62.0% of the variance of the overall QoL. Conclusions: The relationship between patients and physicians and maintaining relational continuity with the medical providers directly affect patients’ QoL during hospitalization and should be prioritized clinically. Timely interventions should be provided for older adult patients with T2DM, depression, or an inability to exercise to maintain their QoL.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Continuity of Care and the Quality of Life among Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Taiwan

Hsieh

Yang

et al. 2020

Healthcare

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“…A significant correlation between GDS-15 score and body mass index has been observed in older people with T2D. 42 Similarly, Mut-Vicu and colleagues 43 demonstrated that for every increase of 1 kg/m 2 in body mass index, the odds of depression (evaluated using the Patient Health Questionnaire-9 44 ) increased by 10.1% in older adults with T2D. In contrast, Cardenas and colleagues 45 revealed no association between body mass index and major depression (evaluated using the Patient Health Questionnaire-9 44 ) among community-dwelling older Latino adults diagnosed with T2D and mild to moderately severe depression.…”

Section: Discussionmentioning

confidence: 94%

Association between depressive symptoms and pulse wave velocity is mediated by increased adiposity in older adults with type 2 diabetes

Moh

Low

et al. 2021

jpn

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Background: Studies investigating the association between depression and aortic stiffness in older patients with type 2 diabetes are lacking. We postulated an association between depressive symptoms and aortic stiffness, and this relationship may be mediated by increased adiposity. Methods: We analyzed participants with type 2 diabetes aged 55 years or older (n = 958). We measured aortic stiffness using carotid-femoral pulse wave velocity (cut-off ≥ 12 m/s) using the tonometry method. We defined depressive symptoms as a score of greater than 5 on the Geriatric Depression Scale-15 (GDS-15). Adiposity indices we assessed were body mass index, waist circumference, waistto-height ratio, visceral fat area and fat mass. Results: Among the participants, 27.2% had aortic stiffness, of whom 6.5% had depressive symptoms. Score on the GDS-15 was correlated with pulse wave velocity, and both variables were correlated with the adiposity markers we analyzed (all p < 0.05). Depressive symptoms were associated with pulse wave velocity (B = 1.79, 95% confidence interval [CI] 0.83-2.75) or aortic stiffness (risk ratio 1.60, 95% CI 1.10-2.33) in the unadjusted model. The association persisted after controlling for demographics, duration of diabetes, glycated hemoglobin, comorbidities and medications. Further adjustment for visceral fat area and fat mass in separate models reduced the association between depressive symptoms and pulse wave velocity or aortic stiffness. Mediation models revealed that the mediation proportions of fat mass and visceral fat area on the association between depressive symptoms and pulse wave velocity were 11.8% and 9.7%, respectively. A preliminary analysis of longitudinal data (n = 184) showed similar findings. Limitations: Causality cannot be inferred from the associations we observed. Conclusion: Depressive symptoms are associated with elevated pulse wave velocity in older people with type 2 diabetes, and this relationship may be partially mediated by increased adiposity.

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Demographic, socioeconomic and health determinants of depressive symptoms in adults 50 years and older from Mexico: a secondary data longitudinal analysis from the Mexican Health and Aging Study

Giraldo-Rodríguez,

Torres-Castro,

Roa-Rojas

et al. 2024

BMJ Open

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BackgroundDepression in ageing adults is a public health problem. Worldwide studies have identified social and health risk factors for depressive symptoms. However, little is known about their longitudinal determinants in Mexico.Objectives and settingTo find the prevalence of depressive symptoms and their longitudinal individual and contextual risk factors in Mexican adults aged 50 and older.DesignSecondary data of 6460 persons aged 50 years and older from the Mexican Health and Aging Study were analysed using a ‘between-within’ panel data analysis approach.ResultsThe prevalence of depressive symptoms increased from 35% in 2003 to 38% in 2015. The significantly longitudinal factors associated with these symptoms were getting older (OR 1.02, 95% CI 1.01 to 1.03), being a woman (OR 2.39, 95% CI 2.16 to 2.64), less time spent in formal education (0 years and less than 6 years OR 1.52, 95% CI 1.32 to 1.75 and OR 1.33, 95% CI 1.19 to 1.50, respectively), lower net worth (OR 1.13, 95% CI 1.08 to 1.17), being recently unemployed (OR 1.25, 95% CI 1.10 to 1.25), increased (OR 1.17, 95% CI 1.10 to 1.25) or increasing number (OR 1.23, 95% CI 1.15 to 1.31) of chronic conditions, poor (OR 4.68, 95% CI 4.26 to 5.15) or worsened (OR 1.71, 95% CI 1.61 to 1.81) self-rated health and having impairments on instrumental activities of daily living (IADLs) (OR 2.94 95% CI 2.35 to 3.67) or a new IADL impairment (OR 1.67, 95% CI 1.48 to 1.89), as well as having impairments on ADLs (OR 1.51, 95% CI 1.23 to 1.86) or a new ADL impairment (OR 1.34, 95% CI 1.21 to 1.48).ConclusionsThe prevalence of depressive symptoms in Mexican adults aged 50 and older is high. Our findings show that they are longitudinally associated with the individual’s demographic, socioeconomic, health and disability characteristics. Efforts in public policy should focus on preventing chronic conditions and disability, as well as fighting inequalities to reduce the prevalence of depressive symptoms.

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Factors related to depressive symptoms in older adult patients with type 2 Diabetes Mellitus

Cited by 5 publications

References 27 publications

Continuity of Care and the Quality of Life among Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Taiwan

Continuity of Care and the Quality of Life among Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Taiwan

Association between depressive symptoms and pulse wave velocity is mediated by increased adiposity in older adults with type 2 diabetes

Demographic, socioeconomic and health determinants of depressive symptoms in adults 50 years and older from Mexico: a secondary data longitudinal analysis from the Mexican Health and Aging Study

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