Factors related to barriers and medication adherence in patients with type 2 diabetes mellitus: a cross-sectional study

Zairina, Elida; Nugraheni, Gesnita; Sulistyarini, Arie; Mufarrihah,; Setiawan, Catur Dian; Kripalani, Sunil; Lestari, Safira Indah

doi:10.1007/s40200-021-00961-6

Cited by 14 publications

(6 citation statements)

References 45 publications

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“…This questionnaire contains twelve questions: eight items from the drug use subscale to assess the patient's adherence to using prescribed drugs as directed, and four items from the prescription refill subscale to assess the patient's adherence to refilling his prescription. The ARMS questionnaire has been P-ISSN: 2406-9388 E-ISSN: 2580-8303 translated and validated in several countries, such as Iran, Korea, China, Spain, and Poland (Jin et al, 2016;Kim et al, 2016;González-Bueno et al, 2017;Barati et al, 2018;Lomper et al, 2018;Park et al, 2018Chen et al, 2020Kripalani et al, 2009;Zairina et al, 2022).…”

Section: Methodsmentioning

confidence: 99%

The Effect of Insulin Administration on Medication Adherence in Type 2 Diabetes Mellitus Patients with Neurological Complications

July

Sauriasari²,

Syafhan³

et al. 2022

JFIKI

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Background: Medication adherence is essential to achieving controlled blood sugar in diabetic patients. Insulin generally provides better glycemic control but is considered painful and requires special techniques. Insulin administration in patients with neurological complications requires particular consideration because these complications can cause physical and cognitive barriers. Objective: This study analyses the effect of insulin administration on medication adherence in diabetic patients with neurological complications and the influence of various confounding variables (baseline characteristics, medical and medication history). Methods: This observational study was conducted with a cross-sectional design at a government hospital in East Jakarta from September 2021 to January 2022. The sample was type 2 diabetes mellitus patients with neurological complications who received antidiabetics for at least six months. The neurological complications include central nervous disorders (such as stroke) and peripheral nervous disorders (such as neuropathy). The independent variable was insulin administration, while the dependent variable was adherence, measured using subjective methods [Adherence to Refills and Medications Scale (ARMS)] and objective methods (Medication Refill Adherence (MRA) and HbA1c]. Results: Of 175 respondents, based on the three methods (MRA, ARMS, HbA1c), 13 respondents (7.4%) were adherent, namely one respondent (1.8%) in the insulin group and 12 respondents (10.1%) in the non-insulin group. Insulin administration affects adherence to antidiabetics by 0.123 times (95% CI: 0.015 - 1.024), or patients who use insulin have 87.7% lower adherence controlled by antidiabetic changes and the total number of medicines used. Conclusion: Insulin administration significantly affects medication adherence in diabetes mellitus patients with neurological complications.

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Section: Methodsmentioning

confidence: 99%

The Effect of Insulin Administration on Medication Adherence in Type 2 Diabetes Mellitus Patients with Neurological Complications

July

Sauriasari²,

Syafhan³

et al. 2022

JFIKI

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“…Patient medication compliance has been widely recognized as a growing problem and a major health concern. Evidence has shown that 50% of patients do not follow prescribed medication regimens (Zairina et al, 2022). The factors reported affecting medication compliance were unwanted drug effects, changes in drug regimens, and refilling the prescriptions after they ran out (Zairina et al, 2022).…”

Section: Two Major Challenges In H Pylori Treatment Managementmentioning

confidence: 99%

“…Evidence has shown that 50% of patients do not follow prescribed medication regimens (Zairina et al, 2022). The factors reported affecting medication compliance were unwanted drug effects, changes in drug regimens, and refilling the prescriptions after they ran out (Zairina et al, 2022). Improving medication compliance of patients has become a great challenge for doctors, pharmacists, nurses and other medical personnel (L. C. Li, Han, et al, 2021).…”

Section: Two Major Challenges In H Pylori Treatment Managementmentioning

confidence: 99%

Treatment strategies and pharmacist‐led medication management for Helicobacter pylori infection

Wang

Chen

Pei

et al. 2022

Drug Development Research

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Half of the world's population is Helicobacter pylori carrier. Updated guidelines and consensus have been issued across regions with the main aim of reducing social transmission and increasing H. pylori eradication rate. Although alternative therapies including traditional Chinese medicine and probiotics have also been used to improve H. pylori eradication rate in clinical practice, current mainstream treatment is still dependent on triple and quadruple therapies that includes antibacterial agents (e.g., amoxicillin and furazolidone) and proton pump inhibitor. Researches also assessed the eradication rate of optimized high-dose dual therapy in treating H. pylori infection. With the increase of antibiotic resistance rate, the treatment strategies for H. pylori infection are constantly adjusted and improved. Besides, low medication compliance is another key influencing factor for H. pylori treatment failure. Emerging studies indicate that pharmacists' intervention and new pharmaceutical care methods can enhance patient medication compliance, reduce adverse drug reactions, and improve H. pylori eradication rate. The purpose of this review is to summarize the advances in treating H. pylori infection and highlight the necessity of developing novel strategies to cope with the increasing challenges and to achieve personalized medication. Also, this review attaches great importance to pharmacists in optimizing H. pylori treatment outcomes as a routine part of therapy.

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“…However, research into medication adherence is a way of tracking strategies for dealing effectively with chronic health conditions, since the consequences of non-adherence on the ability to take medication can include sub-optimal responses, disease recurrence, adverse events, increased use of health services, unplanned hospitalizations, increased morbidity and mortality, and increased health care costs. [4][5][6][7][8][9][10] The ability to consume medication and adherence are influenced by factors related to consumers, their therapies, their medical conditions, social factors, healthcare providers and factors related to the healthcare system, and can therefore be interrelated, since non-adherence can result from a patient being unable to follow instructions or the difficulty of removing medication from the packaging, these are factors, among others, that can be identified as barriers to adherence to treatment, thus, the inappropriate use of medication has stimulated research to verify the factors related to barriers. In addition, many adverse health outcomes may be avoidable if appropriate measures are taken to identify these risk factors and optimize the ability to adhere to and use drugs.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with medication adherence and therapeutic barriers: relationship with social support in the elderly / Fatores associados a adesão e barreiras a terapêutica medicamentosa: relação com o apoio social em idosos

Soares,

Pinto Okuno

2024

RPCF

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Objetivo: associar a adesão e as barreiras da terapêutica medicamentosa com o apoio social em idosos. Método: estudo transversal e analítico, realizado em um ambulatório na cidade de São Paulo – SP, com 117 idosos, no período de março a novembro de 2019. Para coleta de dados foram utilizados o teste de Morisky Green (TMG) e a escala Brief Medical Questionnaire, e a Medical Outcomes Study. A correlação entre as variáveis foi realizada pelo teste de Kruskal-Wallis e o teste de Mann-Whitney. Em todas as análises comparativas foi utilizado um nível de significância de 5% e intervalo de confiança de 95%. Resultados: idosos que possuem apoio social na dimensão emocional e de informações apresentaram menores barreiras na adesão dos medicamentos (p=0,0216). Conclusões: esses resultados têm implicações importantes para a prática clínica, pois, os idosos mais vulneráveis com baixo apoio social possuem maiores barreiras ao uso da medicação.

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Factors related to barriers and medication adherence in patients with type 2 diabetes mellitus: a cross-sectional study

Cited by 14 publications

References 45 publications

The Effect of Insulin Administration on Medication Adherence in Type 2 Diabetes Mellitus Patients with Neurological Complications

The Effect of Insulin Administration on Medication Adherence in Type 2 Diabetes Mellitus Patients with Neurological Complications

Treatment strategies and pharmacist‐led medication management for Helicobacter pylori infection

Factors associated with medication adherence and therapeutic barriers: relationship with social support in the elderly / Fatores associados a adesão e barreiras a terapêutica medicamentosa: relação com o apoio social em idosos

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