Factors predicting health-related quality of life following necrotizing fasciitis

Gawaziuk, Justin P.; Strazar, Robert; Cristall, Nora; Logsetty, Sarvesh

doi:10.1016/j.bjps.2018.01.035

Cited by 25 publications

(41 citation statements)

References 23 publications

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“…32 The HRQoL after NSTIs has only been assessed in four prior studies (one qualitative and three quantitative studies with respectively 4.2, 3.2, 4.1, and 5 years follow-up and similar sample sizes ranging from 19 to 56 participants). 14,[33][34][35] The biggest differences between these studies and ours are either the study design (qualitative versus quantitative) or the study population (NSTI of all body regions vs. upper score for NSTIs affecting all body regions are lower than the scores found in our study specifically assessing NSTIs of the upper extremity, which were respectively 80.0, 48.7, and 55.3. Based on this comparison, it could be hypothesized that NSTIs of the upper extremity have less consequences for the eventual HRQoL compared with NSTIs affecting other body regions.…”

Section: Discussioncontrasting

confidence: 73%

Survival and Health-Related Quality of Life after Hospitalization for Necrotizing Soft Tissue Infections of the Upper Extremity: A Long-Term Outcome Study

Nawijn

Verhiel

Nierich

et al. 2022

Journal of Hand and Microsurgery

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Introduction The main aim of the study was to investigate the survival and health-related quality of life (HRQoL) after hospitalization for necrotizing soft tissue infections (NSTIs) of the upper extremity. Materials and Methods A retrospective study with long-term follow-up of patients surviving NSTIs of the upper extremity was performed. Survival and HRQoL after hospital discharge were the primary outcomes. The HRQoL was measured using the 36-item Short Form (SF-36), EuroQoL-5D-5L (EQ-5D), Quick Disability of Shoulder, Arm and Hand (QuickDASH), and numeric rating scales (NRS) for satisfaction with appearance and pain. Results A median of 6.5 years after hospitalization, 81% of the 108 patients survived. The response rate was 45% (n = 38). The SF-36 score was 80 (interquartile range [IQR]: 58–91), the EQ-5D score 1.4 (IQR: 1.2–2.2), the EuroQoL-Visual Analog Scale score 77 (IQR: 67-90), the QuickDASH score 13.6 (IQR: 2.3-30.7), the NRS for satisfaction with appearance 8 (IQR: 7–9), and NRS for pain 1 (IQR: 0-5). Conclusion Six-and-a-half years after the NSTI, 81% of the patients were still alive. General health prior to the NSTI mainly influenced the risk at secondary mortality. In surviving patients, the HRQoL varied widely, but was adversely affected by female sex, intravenous drug use, NSTI type I or III, and longer length of hospital stay.

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Section: Discussioncontrasting

confidence: 73%

Survival and Health-Related Quality of Life after Hospitalization for Necrotizing Soft Tissue Infections of the Upper Extremity: A Long-Term Outcome Study

Nawijn

Verhiel

Nierich

et al. 2022

Journal of Hand and Microsurgery

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“…A recent publication of HRQoL after NSTI as measured with the SF-36 found that both PCSs and MCSs were significantly lower in patients after NSTI. 17 Unfortunately, the scores for the individual SF-36 domains were not reported. Consequently, an exact comparison to the results of our study could not be made.…”

Section: Discussionmentioning

confidence: 99%

“…13 Current knowledge about HRQoL in patients surviving NSTI is still based on a few studies. 16,17 Therefore, this study was initiated. The primary aim of this study was to assess patientreported HRQoL after NSTI.…”

Section: Introductionmentioning

confidence: 99%

Health-Related Quality of Life Is Decreased After Necrotizing Soft-Tissue Infections

Suijker

Vries

Jong

et al. 2020

Journal of Surgical Research

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“…Necrotizing skin and soft tissue infections (NSTIs) are rare, life-threatening bacterial infections resulting in extensive tissue necrosis and destruction. Hospital mortality ranges from 9.3 to 29.3%, with disabling sequelae for 30% of survivors [1–3]. With an incidence of 4/100,000 persons per year [4], initial misdiagnosis is frequent [5], leading to a delayed surgical debridement of infected tissues, one of the main modifiable prognostic factors [6].…”

Section: Introductionmentioning

confidence: 99%

Impact of a multidisciplinary care bundle for necrotizing skin and soft tissue infections: a retrospective cohort study

Urbina

Hua

Sbidian

et al. 2019

Ann. Intensive Care

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BackgroundNecrotizing skin and soft tissue infections (NSTIs) require both prompt medical and surgical treatment. The coordination of multiple urgent interventions by care bundles has improved outcome in other settings. This study aimed to assess the impact of a multidisciplinary care bundle on management and outcome of patients with NSTIs.MethodsPatients with NSTIs admitted between 2006 and 2017 were compared according to admission before or after bundle implementation (2012–2013). This bundle consisted mainly in (1) the creation of a multidisciplinary task force; (2) management guidelines on empirical antibiotics, intensive care unit admission criteria, a triage algorithm to accelerate operating room access; and (3) an active communication policy. Patient recruitment and management were compared between pre- and post-implementation periods. Main outcome was day 60-censored hospital survival.ResultsOverall, 224 patients were admitted: 60 before, 35 during, and 129 after bundle implementation. Admission after implementation was associated with increased yearly admissions (10 [8–13] vs 30 [24–43] patients/year, p = 0.014) and decreased mortality (30 vs 15%, HR = 0.49 [0.26–0.92]; p = 0.026) but was no longer a protective factor for mortality after adjustment on confounding factors (adjusted HR = 0.90 [0.43–1.88], p = 0.780). There was no significant difference regarding time to surgery (0 [0–1] vs 0 [0–1] days, p = 0.192) or rate of antibiotic treatment within 24 h (98% vs 99%, p > 0.99).ConclusionsImplementation of a multidisciplinary care bundle for NSTIs was feasible, but in a retrospective study from an already experienced center was not associated with significantly increased survival after adjustment.

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Factors predicting health-related quality of life following necrotizing fasciitis

Cited by 25 publications

References 23 publications

Survival and Health-Related Quality of Life after Hospitalization for Necrotizing Soft Tissue Infections of the Upper Extremity: A Long-Term Outcome Study

Survival and Health-Related Quality of Life after Hospitalization for Necrotizing Soft Tissue Infections of the Upper Extremity: A Long-Term Outcome Study

Health-Related Quality of Life Is Decreased After Necrotizing Soft-Tissue Infections

Impact of a multidisciplinary care bundle for necrotizing skin and soft tissue infections: a retrospective cohort study

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