Factors predicting chronic pain after open mesh based inguinal hernia repair: ​A prospective cohort study

Pierides, Georgios; Paajanen, Hannu; Vironen, Jaana

doi:10.1016/j.ijsu.2016.03.061

Cited by 32 publications

(14 citation statements)

References 31 publications

(26 reference statements)

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“…11 The introduction of foreign material can produce foreign body reaction 20 with a feeling of discomfort in the groin region, and sometimes the usage of the LWM was associated with less feeling of foreign body than that of the HWM. 8,14,16,21 Our results do not agree with these findings.…”

Section: Discussioncontrasting

confidence: 99%

“…1 Association between higher preoperative groin pain levels and chronic postoperative pain has been noted earlier. 14 Improvement of pain management of inguinal hernia before operation has been advocated but not examined. Some of the etiological factors involved in chronic groin pain are inguinal nerves irritation by the sutures, inflammatory reaction against the mesh, and the incorporation of the inguinal nerves by the scarring process.…”

Section: Discussionmentioning

confidence: 99%

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Randomized Clinical Trial Comparing Low Density versus High Density Meshes in Patients with Bilateral Inguinal Hernia

Carro

Riu

Lojo

et al. 2017

The American Surgeon

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We present a randomized clinical trial to compare postoperative pain, complications, feeling of a foreign body, and recurrence between heavyweight and lightweight meshes in patients with bilateral groin hernia. Sixty-seven patients with bilateral hernia were included in our study. In each patient, the side of the lightweight mesh was decided by random numbers table. Pain score was measured by visual analogue scale, on 1st, 3rd, 5th, and 7th postoperative day, and one year after the surgery. There were no statistically significative differences between both meshes in postoperative complications. About differences of pain average, there were statistically significant differences only on the 1st postoperative day (P <0.01) and the 7th postoperative day (P <0.05). In the review after a year, there were no statistically significative differences in any parameter. In our study, we did not find statistically significative differences between lightweight and heavyweight meshes in postoperative pain, complications, feeling of a foreign body, and recurrence, except pain on 1st and 7th postoperative day.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Randomized Clinical Trial Comparing Low Density versus High Density Meshes in Patients with Bilateral Inguinal Hernia

Carro

Riu

Lojo

et al. 2017

The American Surgeon

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“…thoracotomies, mastectomies) can develop chronic postoperative pain indicating that pain is not a prerequisite for this development. It is known that the pre-operative pain intensity and young age are two predictors for development of chronic postoperative pain (Pierides et al, 2016). Factors such as physical health, mental health, preoperative pain in the surgical field, and preoperative pain are all additional contribution factors (Montes et al, 2015).…”

Section: Common Sensitisation Features Across Chronic Pain Conditionsmentioning

confidence: 99%

Assessment and manifestation of central sensitisation across different chronic pain conditions

Arendt-Nielsen

Morlion

Perrot

et al. 2017

European Journal of Pain

445

443

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Different neuroplastic processes can occur along the nociceptive pathways and may be important in the transition from acute to chronic pain and for diagnosis and development of optimal management strategies. The neuroplastic processes may result in gain (sensitisation) or loss (desensitisation) of function in relation to the incoming nociceptive signals. Such processes play important roles in chronic pain, and although the clinical manifestations differ across condition processes, they share some common mechanistic features. The fundamental understanding and quantitative assessment of particularly some of the central sensitisation mechanisms can be translated from preclinical studies into the clinic. The clinical perspectives are implementation of such novel information into diagnostics, mechanistic phenotyping, prevention, personalised treatment, and drug development. The aims of this paper are to introduce and discuss (1) some common fundamental central pain mechanisms, (2) how they may translate into the clinical signs and symptoms across different chronic pain conditions, (3) how to evaluate gain and loss of function using quantitative pain assessment tools, and (4) the implications for optimising prevention and management of pain. The chronic pain conditions selected for the paper are neuropathic pain in general, musculoskeletal pain (chronic low back pain and osteoarthritic pain in particular), and visceral pain (irritable bowel syndrome in particular). The translational mechanisms addressed are local and widespread sensitisation, central summation, and descending pain modulation. Significance Central sensitisation is an important manifestation involved in many different chronic pain conditions. Central sensitisation can be different to assess and evaluate as the manifestations vary from pain condition to pain condition. Understanding central sensitisation may promote better profiling and diagnosis of pain patients and development of new regimes for mechanism based therapy. Some of the mechanisms underlying central sensitisation can be translated from animals to humans providing new options in development of therapies and profiling drugs under development.

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“…Patient characteristics can also influence analgesic medication intake. There are several predictors of chronic pain including younger age, higher BMI, and being discharged on the day of surgery rather than staying overnight; 15,23 however, the associations between these variables and postoperative pain have not been reported with respect to inguinal hernia repair. In particular, while obesity affects drug volume distribution and modifies anesthetic requirements during surgery, 24 little research has examined the influence of BMI on postoperative analgesic use.…”

Section: Introductionmentioning

confidence: 99%

Open vs Laparoscopic Inguinal Hernia Repair: Influences of Patient Age and BMI on Analgesic Requirements and Hospital Stay Duration

Mwagiru¹,

Larkin²

2020

World Journal of Laparoscopic Surgery With DVD

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Aim:Comparisons between open vs laparoscopic surgical methods for inguinal hernia repair have yielded inconsistent results with respect to patients' pain levels and analgesic requirements post-surgery. This study compared open vs laparoscopic inguinal hernia repair in terms of types and quantity of analgesics administered during the postoperative recovery period and the hospital stay, including the influences of patient characteristics such as age, BMI, and previous inguinal hernia repair. Materials and methods: This was a cross-sectional study of retrospective analysis of data pertaining to inguinal hernia repairs in a rural hospital in Australia. Results: Among 63 patients (60 males), 62% had undergone open and 38% laparoscopic surgery for inguinal hernia repair. Type and dose of analgesic medications given during both the postoperative recovery period and the hospital ward stay and the duration of the hospital stay were not significantly different between open and laparoscopic groups. However, there were significant influences of BMI, with significantly more overweight and obese patients requiring a combination of opioids with nonsteroidal anti-inflammatory drug (NSAID) or paracetamol during the hospital stay, and with obese patients having the longest hospital stay, followed by overweight patients. Patients who had open surgery were significantly older and less likely to have had a previous inguinal hernia repair than those who had laparoscopic surgery, and there was a significant correlation between age and duration of hospital stay. Conclusion:Patient characteristics of age, BMI, and previous inguinal hernia repair are confounding factors when comparing analgesic requirements and hospital stay duration after open vs laparoscopic inguinal hernia repair.

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Factors predicting chronic pain after open mesh based inguinal hernia repair: A prospective cohort study

Cited by 32 publications

References 31 publications

Randomized Clinical Trial Comparing Low Density versus High Density Meshes in Patients with Bilateral Inguinal Hernia

Randomized Clinical Trial Comparing Low Density versus High Density Meshes in Patients with Bilateral Inguinal Hernia

Assessment and manifestation of central sensitisation across different chronic pain conditions

Open vs Laparoscopic Inguinal Hernia Repair: Influences of Patient Age and BMI on Analgesic Requirements and Hospital Stay Duration

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Factors predicting chronic pain after open mesh based inguinal hernia repair: ​A prospective cohort study

Cited by 32 publications

References 31 publications

Randomized Clinical Trial Comparing Low Density versus High Density Meshes in Patients with Bilateral Inguinal Hernia

Randomized Clinical Trial Comparing Low Density versus High Density Meshes in Patients with Bilateral Inguinal Hernia

Assessment and manifestation of central sensitisation across different chronic pain conditions

Open vs Laparoscopic Inguinal Hernia Repair: Influences of Patient Age and BMI on Analgesic Requirements and Hospital Stay Duration

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Factors predicting chronic pain after open mesh based inguinal hernia repair: A prospective cohort study