1993
DOI: 10.1111/j.1600-0528.1993.tb00771.x
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Factors influencing the effectiveness of sealants – a meta‐analysis

Abstract: Meta-analysis of published studies was applied to analyze the effectiveness of fissure sealants in preventing dental caries. Studies were identified by a MEDLINE search, supplemented by a hand search of the references in the articles recovered. All articles were assessed on the basis of quality, and were combined with the Mantel-Haenszel method. The prevented fraction in the exposed population (PF) was estimated using pooled relative risk. Heterogeneity of the effect and publication bias were also analyzed. Tw… Show more

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Cited by 112 publications
(64 citation statements)
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“…Additionally, in order to reduce selection bias, trials that seek to assess the caries-preventive effect of fissure sealants should aim to recruit children soon after the eruption of their first molars. Previous publications (2,12,40) have highlighted a number of factors that could potentially affect the cariespreventive effect of fissure sealants. Only some of the trials have reported on these factors.…”
Section: Discussionmentioning
confidence: 99%
“…Additionally, in order to reduce selection bias, trials that seek to assess the caries-preventive effect of fissure sealants should aim to recruit children soon after the eruption of their first molars. Previous publications (2,12,40) have highlighted a number of factors that could potentially affect the cariespreventive effect of fissure sealants. Only some of the trials have reported on these factors.…”
Section: Discussionmentioning
confidence: 99%
“…An alternative to allow a more efficient biofilm control in this area is the use of dental sealants. 43 The sealing of occlusal surfaces in a preventive approach has shown positive results (caries risk reduction of 33-65%); [44][45][46][47][48] however, it will depend on a series of variables. Ahovuo-Saloranta et al, 48 through a systematic review of the literature, showed that the effectiveness of sealants is obvious for high caries-risk individuals, but information on the benefits of sealing to patients with different caries-risk levels is lacking.…”
Section: Biofilm Control and Heath Promotionmentioning
confidence: 99%
“…A systematic review published in the early 1990s found that the preventive fraction (PF), that is the proportion of occlusal decay prevented, among children receiving a one-time application of autopolymerizing sealant was 71%. 5 This preventive fraction PF is given by (I 0 -I 1 )/ I 0 where I 1 is the incidence of dental caries in the group treated with fissure sealants and I 0 is the incidence in the control group. Ultra-violet light polymerized sealant had a PF of 46%, but this 'first generation' product is no longer available.…”
Section: Effectiveness Of Sealantsmentioning
confidence: 99%