Coronary heart diseases, commonly manifesting as Myocardial Infarction, remains as a leading cause of death and disability worldwide. It also contributes to the rising economic burden, with an overall cost expenditure reaching $219 billion every year in the United States. Therefore, prompt return-to-work following myocardial infarction is needed to reduce this financial burden. However, there is a lack of study investigating how variables are linked to return-to-work rate in these patients. This study aims to provide a review of the factors that affects return-to-work duration and quality in previous researches. It is expected that this literature may serve as a guide for physicians and stakeholders to place more focus on patients with factors leading to less favorable conditions.