Factors Influencing Patency of Infrainguinal Bypasses with Polytetrafluoroethylene

Thomas, Bradley G.; Lacroix, Hendrik; Nevelsteen, André; Suy, R

doi:10.1080/00015458.1999.12098486

Acta Chirurgica Belgica

1999

DOI: 10.1080/00015458.1999.12098486

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Factors Influencing Patency of Infrainguinal Bypasses with Polytetrafluoroethylene

Bradley G. Thomas¹,

Hendrik Lacroix²,

André Nevelsteen³

et al.

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Cited by 3 publications

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“…The long-term patency rate of prosthetic femoralpopliteal bypass grafts remains low. Studies have reported 3-year primary patencies of 43% 1 for direct distal-end prosthetic infrapopliteal bypasses and 45% 2 for below-knee prosthetic femoral-popliteal bypasses and 5-year primary patencies of 41% 3 for prosthetic distal-end infrainguinal bypasses. Above-knee prosthetic femoral-popliteal bypass procedures for intermittent claudication have reported 2-year primary patencies of 58%.…”

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confidence: 99%

Computational investigations of a new prosthetic femoral-popliteal bypass graft design

O'Brien

Grace

Walsh

et al. 2005

Journal of Vascular Surgery

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The search for a viable alternative to traditional end-to-side anastomosis for prosthetic femoral-popliteal bypass procedures is ongoing. Prosthetic femoral-popliteal bypass procedures have low long-term patency rates, and there is a need for methods that increase the life span of the procedure. Although research is progressing on a variety of different fronts, this study is significant in that it reports on in vitro tests on a potential device that may increase bypass patency. The device is simple, may be manufactured from clinically proven materials, does not require any additional training in its use, and combines attributes of end-to-side anastomoses with those of end-to-end anastomoses. In addition, the design concept behind the device, the natural bifurcation, may be relevant in other aspects of cardiovascular surgery.

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mentioning

confidence: 99%

Computational investigations of a new prosthetic femoral-popliteal bypass graft design

O'Brien

Grace

Walsh

et al. 2005

Journal of Vascular Surgery

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Early Graft, Limb and Mortality Outcomes from the Omniflow II Bio-Synthetic Graft

Evans

Buchanan

Goel

et al. 2022

Annals of Vascular Surgery

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Predictors of Time to Graft Failure Following Infrainguinal Arterial Reconstruction

Hallihan¹,

Choileain²,

Myers³

et al. 2011

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Background and purpose Infrainguinal arterial reconstruction increases limb salvage rates, however, the fac- tors that predict time to graft failure remain ill-defined. The aim of this study was to define such predictors. Methods A retrospective analysis of infrainguinal arterial reconstructions performed for symptomatic pe- ripheral arterial disease refractory to medical/interventional therapies over a 6 year period was performed. Demographics and adverse outcomes were analysed and statistical significance was determined using Chi-squared analysis, the Student t test and the Wilcoxon signed-rank test. Main findings 170 procedures were analysed. The male to female ratio was 4:3. The median age was 70.1 years. The post-operative com- plication rate was 12%. On univariate analysis, female gender, the use of a synthetic graft, and the presence of critical ischaemia at the time of surgery were predictive of time to graft failure (ρ ≤ 0.05, ρ ≤ 0.03, ρ ≤ 0.02 respectively). On multivariate analysis, the 3 most significant predictors were the occurrence of a post-operative complication, female gender and a high ASA grade. The presence of diabetes mellitus and smoking did not adversely affect graft outcome, (ρ ≤ 0.23, ρ ≤ 0.20 respectively). Conclusion This study suggests that female gender adversely affects graft patency while a history of smoking and the presence of diabetes mellitus do not. Our findings also suggest that the occurrence of a post-operative complication, and a high ASA grade at time of surgery are additional important predictors of early and late graft failure

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Factors Influencing Patency of Infrainguinal Bypasses with Polytetrafluoroethylene

Cited by 3 publications

References 19 publications

Computational investigations of a new prosthetic femoral-popliteal bypass graft design

Computational investigations of a new prosthetic femoral-popliteal bypass graft design

Early Graft, Limb and Mortality Outcomes from the Omniflow II Bio-Synthetic Graft

Predictors of Time to Graft Failure Following Infrainguinal Arterial Reconstruction

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