Factors influencing opioid‐taking self‐efficacy and analgesic adherence in Taiwanese outpatients with cancer

Liang, Shu‐Yuan; Yates, Patsy; Edwards, Helen; Tsay, Shiow‐Luan

doi:10.1002/pon.1326

Cited by 42 publications

(35 citation statements)

References 28 publications

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“…This trend towards decreased adherence in the propranolol group may be due to increased side effects and/or a lack of pain relief efficacy. 42-45 The overall reduced adherence in this study vs. other studies may also be due to the relatively low socioeconomic status of the patient population. 46,47 …”

Section: Discussioncontrasting

confidence: 51%

Results of a Pilot Multicenter Genotype-based Randomized Placebo-controlled Trial of Propranolol to Reduce Pain After Major Thermal Burn Injury

Orrey

Halawa

Bortsov

et al. 2015

The Clinical Journal of Pain

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Background Results of previous studies suggest that β-adrenoreceptor activation may augment pain, and that β-adrenoreceptor antagonists may be effective in reducing pain, particularly in individuals not homozygous for the catechol-O-methyltransferase (COMT) high activity haplotype. Methods Consenting patients admitted for thermal burn injury at participating burn centers were genotyped; those who were not high activity COMT homozygotes were randomized to propranolol 240mg/day or placebo. Primary outcomes were study feasibility (consent rate, protocol completion rate) and pain scores on study days 5-19. Secondary outcomes assessed pain and posttraumatic stress disorder (PTSD) symptoms 6 weeks post-injury. Results Seventy-seven (61/79) percent of eligible patients were consented and genotyped, and 77% (47/61) were genotype-eligible and randomized. Ninety-one percent (43/47) tolerated study drug and completed primary outcome assessments. In intention to treat and per protocol analyses, patients randomized to propranolol had worse pain scores on study days 5-19. Conclusions Genotype-specific pain medication interventions are feasible in hospitalized burn patients. Propranolol is unlikely to be a useful analgesic during the first few weeks after burn injury.

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Section: Discussioncontrasting

confidence: 51%

Results of a Pilot Multicenter Genotype-based Randomized Placebo-controlled Trial of Propranolol to Reduce Pain After Major Thermal Burn Injury

Orrey

Halawa

Bortsov

et al. 2015

The Clinical Journal of Pain

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show abstract

“…Full details of the sample have been reported elsewhere (Liang, et al, 2008;Liang, et al, 2010a;Liang, et al, 2011b). This paper reports findings of descriptive analyses of participants' responses to the relationship between belief about opioids, opioid adherence and pain experience.…”

Section: Methodsmentioning

confidence: 99%

Relationship Between Belief about Analgesics, Analgesic Adherence and Pain Experience in Taiwanese Cancer Outpatients

Shen¹,

Chen²,

Tsay³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Social and behavioral scientists have proposed that a person's belief system crucially influences his or her behaviour, and therefore may affect outcomes of pain management. The purpose of this study was to explore the relationship between analgesic beliefs, analgesic adherence and pain experience amongst Taiwanese cancer outpatients. The cross-sectional study included 92 oncology outpatients in two teaching hospitals in the Taipei area of Taiwan. The research instruments included the Pain Opioid Analgesic Beliefs Scale-Cancer (POABS-CA), opioid adherence, and the Brief Pain Inventory-Chinese (BPI-Chinese). Beliefs about pain and opioids demonstrated a significant relationship with patients' opioid adherence (r = -0.30, p < 0.01). The more negative beliefs regarding opioids and pain the patient had, the worse their adherence to around the clock (ATC) analgesic regimen. However, there was no significant correlation between opioid belief and pain experience. As well, there were no significant relationships between adherence to opioid regimen and any of the measures of pain experience. The study highlights the potential importance of a patient's pain and opioid beliefs in adherence to pain medication.

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“…Patient behaviors associated with pain medications are typically studied as “adherence,” (12-15), narrowly defined as the “self-administration of medications in prescribed amounts and at prescribed intervals” (13, p. 205) or “nonadherence,” such as avoiding, forgetting, or stopping the medication, or altering the dose (16-18). However, a few researchers recently examined medication management by patients and/or family caregivers as a broader and more complex activity than simply adherence.…”

Section: Introductionmentioning

confidence: 99%

Pain Medication Management Processes Used by Oncology Outpatients and Family Caregivers Part I: Health Systems Contexts

Schumacher

Clark

West

et al. 2014

Journal of Pain and Symptom Management

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Context Oncology patients with persistent pain treated in outpatient settings and their family caregivers have significant responsibility for managing pain medications. However, little is known about their practical, day-to-day experiences with pain medication management. Objective To describe day-to-day pain medication management from the perspectives of oncology outpatients and their family caregivers who participated in a randomized clinical trial of a psycho-educational intervention called the Pro-Self© Plus Pain Control Program. In this article, we focus on pain medication management by patients and family caregivers in the context of multiple, complex health systems. Methods We qualitatively analyzed audio-recorded intervention sessions that included extensive dialogue between patients, family caregivers, and nurses about pain medication management during the 10-week intervention. Results The health systems context for pain medication management included multiple complex systems for clinical care, reimbursement, and regulation of analgesic prescriptions. Pain medication management processes particularly relevant to this context were getting prescriptions and obtaining medications. Responsibilities that fell primarily to patients and family caregivers included facilitating communication and coordination among multiple clinicians, overcoming barriers to access, and serving as a final safety checkpoint. Significant effort was required of patients and family caregivers to insure safe and effective pain medication management. Conclusion Health systems issues related to access to needed analgesics, medication safety in outpatient settings, and the effort expended by oncology patients and their family caregivers require more attention in future research and healthcare reform initiatives.

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Factors influencing opioid‐taking self‐efficacy and analgesic adherence in Taiwanese outpatients with cancer

Abstract: The study highlights the potential importance of a patient's self-efficacy beliefs in adherence to medication and key pain outcomes.

Cited by 42 publications

References 28 publications

Results of a Pilot Multicenter Genotype-based Randomized Placebo-controlled Trial of Propranolol to Reduce Pain After Major Thermal Burn Injury

Results of a Pilot Multicenter Genotype-based Randomized Placebo-controlled Trial of Propranolol to Reduce Pain After Major Thermal Burn Injury

Relationship Between Belief about Analgesics, Analgesic Adherence and Pain Experience in Taiwanese Cancer Outpatients

Pain Medication Management Processes Used by Oncology Outpatients and Family Caregivers Part I: Health Systems Contexts

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