Factors Influencing COVID-19 Vaccine Acceptance in High Income Countries Prior to Vaccine Approval and Rollout: A Narrative Review

Steffens, Maryke S.; Bullivant, Bianca; Bolsewicz, Kasia; King, Catherine; Beard, Frank

doi:10.3389/ijph.2022.1604221

Cited by 20 publications

(20 citation statements)

References 49 publications

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“…Studies among Africans have shown that HCWs themselves are resistant to the vaccine with their information being obtained from unreliable sources such as social media, friends and family [63,64]. Safety concerns, insufficient or inaccurate information, lack of trust in the government's capacity to manage, and personal beliefs are factors that have been reported to influence the acceptance or resistance of HCWs to the vaccine [65][66][67]. The likelihood of such health workers passing on information to the populace with content that may be tainted with their own beliefs and inaccuracies can contribute to making those who interact with them resistant to the vaccine.…”

Section: Discussionmentioning

confidence: 99%

The impact of information sources on COVID-19 vaccine hesitancy and resistance in sub-Saharan Africa

et al. 2023

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Background Vaccination remains the most powerful weapon against the emergence of new variants of coronavirus (COVID-19). However, false information about COVID-19 vaccines through various platforms including social media remains a major threat to global public health. This study examined the impact of information sources on COVID-19 vaccine hesitancy and resistance in sub-Saharan Africa (SSA). Methods A validated web-based cross-sectional study was conducted from 14 March to 16 May 2021, and was administered in both French and English to 2572 participants aged 18 years and over. Data on sociodemographic characteristics, medical and vaccination history, and the information sources (mainstream media and social media) used by the participants during the pandemic were obtained. There were three main outcomes: The vaccinated group were those who responded in the affirmation (Yes) to the question of whether they have been vaccinated against COVID-19. Those who responded ‘not sure’ or ‘no’ to the question were then asked if they were willing to be vaccinated when the vaccine became available in their home countries. The responses to this follow-up question were used to derive the second and third outcome variables of ‘vaccine hesitancy’ and ‘vaccine resistance’, respectively. A series of logistic regression analyses were used to examine the impact of information sources on the three main outcomes. Results The prevalence of COVID-19 vaccine hesitancy among the participants was lowest among newspaper readers (42%) and highest among TV (72%) and social media users (73%). The prevalence of COVID-19 vaccine-resistance was also lowest among newspaper readers (37%) but highest among social media users (87%). Multivariate analyses revealed that compared to those who did not use these information sources, SSA participants who relied on the radio (aOR 0.83, 95%CI = 0.70, 0.99), TV (aOR 0.80, 95%CI = 0.65, 0.97) and social media (aOR 0.79, 95%CI = 0.65, 0.97) for information during the pandemic were less likely to be hesitant towards taking the vaccines. However, social media users (aOR 2.13, 95%CI = 1.62, 2.80), those who watched TV (aOR 1.40, 95%CI =1.08, 1.80), relied on healthcare workers (HCWs: aOR 1.32, 95%CI = 1.07, 1.63) and families/friends (aOR 1.31, 95%CI = 1.06, 1.61) for COVID-19 related information during the pandemic were more likely to resist taking the COVID vaccines in this study. Participants who relied on the newspaper for information during the pandemic were less likely to resist the vaccines (aOR 0.77, 95%CI = 0.62, 0.95) compared to non-readers of a newspaper. Conclusion We found that all six information sources except radio were strong predictors of the resistance towards COVID-19 vaccination. Further research on how these channels can be used to improve the availability of reliable healthcare information is needed. Investments in these resources will protect people and empower them to make appropriate choices about their health.

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Section: Discussionmentioning

confidence: 99%

The impact of information sources on COVID-19 vaccine hesitancy and resistance in sub-Saharan Africa

et al. 2023

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“…Higher income countries and citizens reporting trust in the government's recommendations were more likely to accept the vaccine [24]. Among the high-income countries, commonly reported reasons for denying vaccination were issues regarding vaccine safety and efficacy, the perception of being at low risk of severe infection, and low levels of trust in state authorities or other institutions [25]. Significant heterogeneity regarding vaccine acceptance was seen among health workers from countries with high-income versus low-to middle-income countries, with the former reporting a higher propensity to accept the vaccine [26].…”

Section: Introductionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Primary Care Physicians towards COVID-19 in Greece: A Cross-Sectional Study

et al. 2022

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The aim of this study was to investigate the knowledge, attitudes, and practices of primary care physicians and residents towards the COVID-19 pandemic in Greece. A cross-sectional questionnaire-based study was conducted in Greece during March 2021. The population frame for the study was a list of currently practicing primary care physicians and residents who were registered within one of the main associations of general/family medicine in Greece. Hierarchical multiple logistic regression analysis was performed for practices at higher levels (vs. lower) in relation to knowledge, attitudes, and general characteristics of participants. Overall, 194 participants completed the survey (e-response rate: 38.4%). In total, 94% of participants were familiar with official recommendations regarding SARS-CoV-2, and 88.7% were vaccinated against SARS-CoV-2 or promptly intended to be. Physicians working in the private sector had a higher average practices score when compared to physicians working in the public sector (87.6 vs. 81.9, p < 0.05). Higher levels of attitudes predicted greater odds for higher levels of practices (odds ratio = 4.18, p < 0.05). Despite the relatively high COVID-19 vaccination rate of physicians, several participants were unvaccinated due to a then unscheduled first dose appointment. Attitudes were the only determinant for more proper practices towards the prevention of COVID-19.

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“…[41] . where another Chinese study had acceptance rate of (82.5%) [42] , this shows high-income countries have high acceptance of the vaccine possibly due to higher perception of COVID-19 infection as well as trust in the health o cials [43] . Our acceptance result agreed with a study conducted in Saudi Arabia (64.9%) [44] , in contrast Lebanon and Egypt had lower acceptance rate of (58%), (21%) respectively [45,40] .…”

Section: Resultsmentioning

confidence: 86%

Knowledge, Attitudes and Acceptance towards COVID-19 Vaccination among Health Care Workers in Mukalla city-YEMEN: an analytical cross-sectional study

Bnqadeem

Alsabban

Bokir

et al. 2022

Preprint

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Background COVID-19 vaccination is one of the greatest public health interventions to reduce the burden of the COVID-19 pandemic. Yemen began on April 2021 to vaccinate healthcare workers for COVID-19 with the vaccine. However, the media's negative portrayal of vaccines safety and efficacy has led to concerns regarding the acceptance of the vaccine. Therefore, our study aimed to assess knowledge, attitudes and acceptance towards COVID-19 Vaccination among HCWs in Mukalla city-Yemen. Methods An analytical cross-sectional study was conducted using convenience sampling method in Mukalla city among healthcare workers from April 2022 to May 2022. Data were collected by a self-administered questionnaire. A Chi-square test was used to assess the association between independent variables (demographic) and dependent variables (knowledge, attitude and acceptance). Correlation between knowledge and attitude levels with rate of acceptance was assessed using Pearson correlation coefficient. Results 449 respondents were included in the final analysis, of which 237 (52.8%) were males and 212 (47.2%) were females, with a mean age ± SD of 31.0 ± 7.6 years. The overall results regarding knowledge, attitude, and acceptance rates of the COVID-19 vaccines were 65.3% 63.7% and 68.8% (with an efficacy of 90%), respectively. Acceptance was statistically associated with participants’ job, vaccination state, whether they were dealing with suspected cases of COVID-19 and their source of COVID-19 related information (p-value < 0.05). level of acceptance was moderately correlated with attitude level (r = 0.527). Conclusion Healthcare workers were found to have a moderate level of knowledge and attitude toward COVID-19 vaccination. However, acceptance rate was scaling down according to vaccine efficacy. Many demographic characteristics were significantly associated with acceptance of COVID-19 vaccination.

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Factors Influencing COVID-19 Vaccine Acceptance in High Income Countries Prior to Vaccine Approval and Rollout: A Narrative Review

Cited by 20 publications

References 49 publications

The impact of information sources on COVID-19 vaccine hesitancy and resistance in sub-Saharan Africa

The impact of information sources on COVID-19 vaccine hesitancy and resistance in sub-Saharan Africa

Knowledge, Attitudes, and Practices of Primary Care Physicians towards COVID-19 in Greece: A Cross-Sectional Study

Knowledge, Attitudes and Acceptance towards COVID-19 Vaccination among Health Care Workers in Mukalla city-YEMEN: an analytical cross-sectional study

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