Factors influencing adherence to cancer treatment in older adults with cancer: a systematic review

Puts, Martine; Tu, Hung‐Ming; Tourangeau, Ann E.; Howell, Doris; Fitch, Margaret I.; Springall, Elena; Alibhai, Shabbir M.H.

doi:10.1093/annonc/mdt433

Cited by 180 publications

(161 citation statements)

References 65 publications

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“…A lightweight and wearable system would avoid uncomfortable breast compression and follow patient breathing and motion, allowing patient postural changes during the treatment, thereby improving comfort [30], facilitating treatment persistency, and therapeutic adherence [29]. The wearable device may contribute towards delivering hyperthermia treatments in a repeatable manner over the course of several radiation and/or chemotherapy fractions.…”

Section: Discussionmentioning

confidence: 99%

“…An ergonomically shaped and wearable system in close proximity to the breast would offer enhanced energy deposition, reduced power requirements, and increased comfort, which would facilitate treatment delivery, improve therapeutic adherence and patient treatment persistence [29]. Stauffer et al [30] developed a conformal array of microstrip antennas for hyperthermia treatment of large surfaces with superficial chest wall disease (520 mm depth).…”

Section: Introductionmentioning

confidence: 99%

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Design of a compact antenna with flared groundplane for a wearable breast hyperthermia system

Curto

Prakash

2015

International Journal of Hyperthermia

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Purpose: Currently available microwave hyperthermia systems for breast cancer treatment do not conform to the intact breast and provide limited control of heating patterns, thereby hindering an effective treatment. A compact patch antenna with a flared groundplane that may be integrated within a wearable hyperthermia system for the treatment of the intact breast disease is proposed. Materials and methods: A 3D simulation-based approach was employed to optimise the antenna design with the objective of maximising the hyperthermia treatment volume (41 C iso-therm) while maintaining good impedance matching. The optimised antenna design was fabricated and experimentally evaluated with ex vivo tissue measurements. Results: The optimised compact antenna yielded a À10 dB bandwidth of 90 MHz centred at 915 MHz, and was capable of creating hyperthermia treatment volumes up to 14.4 cm 3 (31 mm Â 28 mm Â 32 mm) with an input power of 15 W. Experimentally measured reflection coefficient and transient temperature profiles were in good agreement with simulated profiles. Variations of + 50% in blood perfusion yielded variations in the treatment volume up to 11.5%. When compared to an antenna with a similar patch element employing a conventional rectangular groundplane, the antenna with flared groundplane afforded 22.3% reduction in required power levels to reach the same temperature, and yielded 2.4 times larger treatment volumes. Conclusion:The proposed patch antenna with a flared groundplane may be integrated within a wearable applicator for hyperthermia treatment of intact breast targets and has the potential to improve efficiency, increase patient comfort, and ultimately clinical outcomes. KeywordsBreast cancer treatment, flared groundplane, microwave hyperthermia, patch antenna, wearable medical devices History

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Design of a compact antenna with flared groundplane for a wearable breast hyperthermia system

Curto

Prakash

2015

International Journal of Hyperthermia

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“…Furthermore, cognitive impairment may impact adherence to cancer treatment. Nonadherence to cancer treatment in older adults is not uncommon [100]. With the increase in oral chemotherapy agents and targeted therapy, adherence to treatment becomes the responsibility of the older adult (or caregiver) [101][102][103].…”

Section: Cognitive Functionmentioning

confidence: 99%

How to Implement a Geriatric Assessment in Your Clinical Practice

et al. 2014

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Cancer is a disease that mostly affects older adults. Other health conditions, changes in functional status, and use of multiple medications change the risks and benefits of cancer treatment for older adults. Several international organizations, such as the International Society of Geriatric Oncology, the European Organization for Research and Treatment of Cancer, recommend the conduct of a geriatric assessment (GA) for older adults with cancer to help select the most appropriate treatment and identify any underlying undetected medical, functional, and psychosocial issues that can interfere with treatment. The aim of this review is to describe what a GA is and how to implement it in daily clinical practice for older adults with cancer in the oncology setting. We provide an overview of commonly used tools. Key considerations in performing the GA include the resources available (staff, space, and time), patient population (who will be assessed), what GA tools to use, and clinical follow‐up (who will be responsible for using the GA results for developing care plans and who will provide follow‐up care). Important challenges in implementing GA in clinical practice include not having easy and timely access to geriatric expertise, patient burden of the additional hospital visits, and establishing collaboration between the GA team and oncologists regarding expectations of the population referred for GA and expected outcomes of the GA. Finally, we provide some possible interventions for problems identified during the GA.

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“…These studies on adherence also point out that negative or neutral beliefs about the value of the treatment were associated with greater non-adherence and nonpersistence, as well as a lack of immediate treatment effect and misconceptions about the treatment effect [7]. In these studies there is an underlying assumption that Black men have negative health beliefs (non-western beliefs about modern medicine) and also suffer from significant misconceptions about treatment hence, non-adherence is high.…”

Section: Introductionmentioning

confidence: 98%

“…Studies on adherence to treatment suggest that for Black people, non-adherence is common and consequently decreased survival, higher recurrence/ treatment failure rates and increased health care costs [7]. These studies on adherence also point out that negative or neutral beliefs about the value of the treatment were associated with greater non-adherence and nonpersistence, as well as a lack of immediate treatment effect and misconceptions about the treatment effect [7].…”

Section: Introductionmentioning

confidence: 99%

Reproductive cancers among South African Black men: A scoping review protocol

Munatswa¹,

Nduna²,

Nkomo³

et al. 2018

Preprint

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Background: The absence of information on reproductive cancer in Black men in South Africa creates a knowledge gap about health outcomes. Consequently, it is necessary to map the existing information in order to formulate research that addresses the knowledge gap. To establish the range, nature and extent of published research on reproductive cancer in Black men in South Africa, an intensive scoping literature search has been designed.

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Factors influencing adherence to cancer treatment in older adults with cancer: a systematic review

Cited by 180 publications

References 65 publications

Design of a compact antenna with flared groundplane for a wearable breast hyperthermia system

Design of a compact antenna with flared groundplane for a wearable breast hyperthermia system

How to Implement a Geriatric Assessment in Your Clinical Practice

Reproductive cancers among South African Black men: A scoping review protocol

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