Factors Influence Lymph Node Retrieval after Resection for Rectal Cancer

Elsheikh, Somaia; M, Abed Zaitoun

doi:10.21767/2572-309x.100013

Cited by 2 publications

(2 citation statements)

References 38 publications

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“…This contrasts with a median of 12 lymph nodes counted in the study by da Costa et al in the Netherlands [15]. About 17% of our colectomies had a minimum of 12 lymph nodes and this is similar though slightly higher than the result of the study by Orsenigo et al in Milan, but lower than 49% documented by Elsheikh and Zaitoun in Nottingham [17,18]. Examining a minimum of 10 lymph nodes increased the percentage to 25.8% in the present study.…”

Section: Discussioncontrasting

confidence: 82%

Audit of Lymph Node Sampling in Colorectal Carcinoma Resections-implication for Prognosis and Management

Ezenkwa

Odigwe

Omenai

et al. 2021

JCTI

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Aims: To review lymph node yield in colorectal carcinoma (CRC) resections and its associated factors in a Nigerian Teaching Hospital practice. Study design: This was a retrospective cross-sectional study. Place and duration of study: Department of Pathology, University College Hospital Ibadan Nigeria and colectomies from January 2014 to December 2018 were reviewed. Methodology: Surgical Pathology reports of CRC resections at the University College Hospital Ibadan over 5 years (2014-2018) were reviewed. Colectomy lengths, tumour location (colon/rectum), tumour size, comment on presence of lymph node (yes/no), lymph node count, presence of attached mesentery (yes/no), histological subtype, tumour grade, presence of tumour-positive node and count, and pT stage were documented. Fisher’s Exact test was employed to test the effects of these variables on presence of lymph node and tumour-positive node at histology using SPSS 20. Significance level was set at P < .05. Results: Of 66 histology reports retrieved, 62 (93.9%) had comments on search for lymph nodes and attached mesentery was documented in 25 (37.9%). The median colectomy length and tumour size were 25cm (6cm-152cm) and 6.75cm (3-30cm) respectively. Lymph nodes were present in 52 (78.8%) specimens; 28 (53.8%) of these had tumour-positive lymph nodes. Adenocarcinoma NOS was the commonest histological subtype 53 (80.3%), mucinous carcinoma 12 (18.2%) and signet ring carcinoma 1 (1.5%). Eighteen, 9 and 1of adenocarcinoma NOS, mucinous carcinoma, and signet ring carcinoma respectively had tumour-positive lymph nodes. Finding of lymph node was significantly associated with comment on search for lymph node (p < .01) while finding tumour-positive nodes was associated with histological subtype, presence of mesentery, late tumour stage and lymph node count ≥ 12 (p < .05). Conclusion: If lymph nodes were present, more than likely there will be metastatic involvement. To increase Lymph node yield in CRC resections, submission of mesentery and search for lymph nodes is indicated. When nodes are absent, a mention is required for practice audit. It is imperative to include both clinical and grossing notes for lymph nodes to certify and guide precise staging of the cancer.

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Section: Discussioncontrasting

confidence: 82%

Audit of Lymph Node Sampling in Colorectal Carcinoma Resections-implication for Prognosis and Management

Ezenkwa

Odigwe

Omenai

et al. 2021

JCTI

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“…11 Total lymph node (TLN) In the present study, the laparoscopic rectal resections had a significantly longer operating time than open resections. This could be assigned to the learning curve of the operating team.…”

Section: Rectal Carcinomamentioning

confidence: 64%

Comparison of short-term outcomes following open and laparoscopic resections for colorectal malignancies

Keerthi¹,

Shankar²,

Ganesh³

et al. 2017

Int J Res Med Sci

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Background: The laparoscopic approach for colorectal cancers are still a matter of controversy. In the present study, we tried to compare the laparoscopy with open methods of colorectal resections.Methods: Retrospective study where patients diagnosed with colorectal cancer in our hospital from year 2014 January to December 2016 were taken. Total number of cases were 69 of which, the total number of right colon cases were 26. Out of twenty-six, 12 underwent open procedure and 14 underwent laparoscopic resections. Total number of left colon cancers were 09. Of these, 2 underwent open and 7 underwent laparoscopic procedure. Thirty-four (34) rectal cancers were included in the study. Of these, 12 underwent open rectal procedures and 22 underwent laparoscopic resections. Multiple parameters like duration of surgery, post-operative complications, postoperative stay, pathological T staging, lymph node yield, positive nodes, distal resection margins, circumferential radial margins were compared.Results: Operating time was significantly shorter in open procedure than laparoscopic surgery in both rectal resection and right hemicolectomies. The postoperative stay was significantly shorter in laparoscopic right hemicolectomy compared to open procedure. All other parameters like post-operative complications, T stage, lymph node yield, positive nodes, distal resection margins and CRMs were comparable in both groups. The lymph node yield was similar in upfront and post neoadjuvant carcinoma rectum cases.Conclusions: Laparoscopic colorectal resections have similar rates of complication, with shorter hospital stays with no compromise on oncological clearance with respect to lymph node yield, CRMs, distal resection margins compared to open procedures.

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Factors Influence Lymph Node Retrieval after Resection for Rectal Cancer

Cited by 2 publications

References 38 publications

Audit of Lymph Node Sampling in Colorectal Carcinoma Resections-implication for Prognosis and Management

Audit of Lymph Node Sampling in Colorectal Carcinoma Resections-implication for Prognosis and Management

Comparison of short-term outcomes following open and laparoscopic resections for colorectal malignancies

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