Factors Determining the Contamination of Bone Tissue Procured from Cadaveric and Multiorgan Donors

Bohatyrewicz, Andrzej; Bohatyrewicz, Romuald; Klek, R.; Kamiński, Adam; Dobiecki, Konrad; Białecki, Piotr; Kędzierski, Michał; Zienkiewicz, M.; Dziedzic‐Goclawska, A.

doi:10.1016/j.transproceed.2005.11.087

Cited by 14 publications

(7 citation statements)

References 8 publications

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“…We must bear in mind that the microorganisms which were isolated in our cultures belonged to the gastrointestinal flora, a type uncommonly found in this tissue (Bohatyrewicz et al 2006;Deijkers et al 1997;Ibrahim et al 2004;Ivory and Thomas 1993;Vehmeyer et al 2002). The accidental rupture of a great blood vessel in the knee combined to the positive cultures obtained reinforced the idea of the contaminating of the donor's blood.…”

Section: Discussionmentioning

confidence: 69%

“…The most widely used approach to perform a microbiological test of a recovered allograft is taking tissue samples during surgery for a culture (Bohatyrewicz et al 2006;Forsell and Liesman 2000;Journeaux et al 1999;Vehmeyer et al 2001). The most frequently cultivated microorganisms in samples of bone or tendinous allografts are often bacteria with a low virulence level, mainly cutaneous flora, which are thought to come from the donors themselves or by contamination from the extracting equipment (Deijkers et al 1997;Vehmeyer et al 2002).…”

Section: Discussionmentioning

confidence: 99%

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Contamination of tissue allografts from a deceased donor through haematic dissemination: a case study

Garcia

Olmos-García

et al. 2009

Cell Tissue Bank

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Infection is one of the most dangerous complications that can be seen when implanting bone or tendon allografts from a deceased donor. The most common germs isolated are found among the cutaneous florae, but sometimes they may be present in the bloodstream as a result of severe injuries suffered before the time of the decease. We present a case of contamination of allografts in a musculoskeletal tissue donor deceased after an accident, whose allografts were contaminated by gastrointestinal microorganisms, probably disseminated through the donor's blood.

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Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Contamination of tissue allografts from a deceased donor through haematic dissemination: a case study

Garcia

Olmos-García

et al. 2009

Cell Tissue Bank

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“…A number of other factors also tends to play a role in healing process with the use of grafts. Time interval between procurement and transplantation of graft is an important factor (Bohatyrewicz et al, 2006). It is said that an autogenous bone graft retains its viability for upto 2 hours when kept in normal saline (Laursen et al, 2003).…”

Section: Allogenic Bone Graftsmentioning

confidence: 99%

Current Concepts and Techniques in Enhancement of Fracture Healing in Canines: A Review.

Saharan¹,

VargheseMathew²

2019

IJAR

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Traditionally used metallic implants for fracture stabilisation even though have potential capability for fracture healing have been associated with significant disadvantages like patient incompliance and implant loosening leading to mal union, non-union and dis-union. Veterinary orthopaedics during the last decade has visualised a significant development with respect to use of biomaterials particularly in the field of fracture treatment and stabilisation. A large variety of biomaterials are available in the form of bone grafts and bone substitutes for commercial use to treat significant bone defects due to trauma and to enhance the rate of fracture healing. The present article aims to give an insight into the various bone grafts and bone substitutes available, their potential uses, applications, advantages and limitations in veterinary field.

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“…The theoretical advantage of osteogenic, osteoconductive and osteoinductive properties is diminished through the fact that the respective cells inside the autograft will not survive longer than 2 h [9]. Thus, the time interval between harvesting and transplantation of the graft is an important factor [10]. Autogenous bone grafts retain their viability for 2 h when kept in normal saline [11].…”

Section: Autologous Bone Graftsmentioning

confidence: 99%

Current Concepts in Bone Graft Substitutes

Leteve¹,

Passuti²

2018

NJGC

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Purpose: Bone grafting is still requested to fill bone defects in traumatology, or after tumor removal, but also in orthopedic surgery for spine, arthroplasty revisions, and osteotomies. Due to the limitations of autografts and allografts, and the progress of biomaterial research, a large number of nonhuman bony scaffolds have been developed including synthetic calcium phosphates and highly processed xenografts. The most important parameters for bone ingrowth are the macroporosity of the scaffold with the suitable biological autologous cells and factors, optimal osteoinductive, osteointegrative and osteoconductive properties can be achieved. Methods and Results: The important factors regulating these properties are discussed in this paper, which also reports preclinical and clinical results obtained with such bone graft substitutes. Conclusions: Among different bone graft substitutes available, the porosity, the accessibility of pores, the internal surface exposed to the biological components of bone repair, are present in highly processed bovine hydroxyapatites. Compared to autografts, allografts and synthetic substitutes, they associate an initial conductivity, and a long term stability suitable for some orthopedic indications.

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Factors Determining the Contamination of Bone Tissue Procured from Cadaveric and Multiorgan Donors

Cited by 14 publications

References 8 publications

Contamination of tissue allografts from a deceased donor through haematic dissemination: a case study

Contamination of tissue allografts from a deceased donor through haematic dissemination: a case study

Current Concepts and Techniques in Enhancement of Fracture Healing in Canines: A Review.

Current Concepts in Bone Graft Substitutes

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