Factors Determining Epithelial-Mesenchymal Transition in Cancer Progression
Paulina Tomecka,
Dominika Kunachowicz,
Julia Górczyńska
et al.
Abstract:Epithelial-mesenchymal transition (EMT) is a process in which an epithelial cell undergoes multiple modifications, acquiring both morphological and functional characteristics of a mesenchymal cell. This dynamic process is initiated by various inducing signals that activate numerous signaling pathways, leading to the stimulation of transcription factors. EMT plays a significant role in cancer progression, such as metastasis and tumor heterogeneity, as well as in drug resistance. In this article, we studied mole… Show more
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